Literature DB >> 12675227

Dipeptidyl peptidase IV gene family. The DPIV family.

Tong Chen1, Katerina Ajami, Geoffrey W McCaughan, Mark D Gorrell, Catherine A Abbott.   

Abstract

We have identified three novel members of the DPIV gene family using database mining approaches. Recombinant DP8 shares a post-proline dipeptidyl aminopeptidase activity with the closely related enzymes DPIV and FAP. The similarities between DP8, DP9 and DPIV in tissue expression pattern suggest a potential role for DP8 and DP9 in liver disease, T cell activation and immune function. The role of the two novel enzymes DP8 and DP9 and the other non-enzyme member DPL2 in human disease will be the focus of further studies.

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Year:  2003        PMID： 12675227     DOI： 10.1007/0-306-47920-6_10

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  7 in total

1.  DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channels.

Authors:  Henry H Jerng; Aaron D Lauver; Paul J Pfaffinger
Journal:  Mol Cell Neurosci       Date:  2007-03-23       Impact factor: 4.314

Review 2.  Potential disease biomarkers: dipeptidyl peptidase 4 and fibroblast activation protein.

Authors:  Roger Yazbeck; Simone E Jaenisch; Catherine A Abbott
Journal:  Protoplasma       Date:  2017-06-16       Impact factor: 3.356

3.  Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties.

Authors:  Henry H Jerng; Kumud Kunjilwar; Paul J Pfaffinger
Journal:  J Physiol       Date:  2005-08-25       Impact factor: 5.182

4.  Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats.

Authors:  Jutta Schade; Michael Stephan; Andreas Schmiedl; Leona Wagner; André J Niestroj; Hans-Ulrich Demuth; Nadine Frerker; Christian Klemann; Kerstin A Raber; Reinhard Pabst; Stephan von Hörsten
Journal:  J Histochem Cytochem       Date:  2007-10-29       Impact factor: 2.479

5.  Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion.

Authors:  Timothy R Dreszer; Gregory D Wall; David Haussler; Katherine S Pollard
Journal:  Genome Res       Date:  2007-09-04       Impact factor: 9.043

6.  Identification and partial characterization of the enzyme of omega: one of five putative DPP IV genes in Drosophila melanogaster.

Authors:  Carol J Chihara; Chunyan Song; Greg LaMonte; Kristina Fetalvero; Kristy Hinchman; Helen Phan; Mario Pineda; Kelly Robinson; Gregory P Schneider
Journal:  J Insect Sci       Date:  2005-11-02       Impact factor: 1.857

7.  Dipeptidyl peptidase 10 (DPP10(789)): a voltage gated potassium channel associated protein is abnormally expressed in Alzheimer's and other neurodegenerative diseases.

Authors:  Tong Chen; Wei-Ping Gai; Catherine A Abbott
Journal:  Biomed Res Int       Date:  2014-06-16       Impact factor: 3.411
  7 in total

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