Literature DB >> 12673749

Experimental model to estimate intestinal viability using charge-coupled device microscopy.

M Yasumura1, Y Mori, H Takagi, T Yamada, K Sakamoto, H Iwata, H Hirose.   

Abstract

BACKGROUND: Intraoperative assessment of intestinal viability following release of strangulation remains difficult. The aim of this study was to establish clinical standards for the evaluation of intestinal viability by charge-coupled device (CCD) microscopy.
METHODS: A rat ileus model with strangulation for between 15 and 120 min was used. The images obtained by CCD microscopy were used to calculate maximum velocity (V (max)) ratio (ratio of V (max) of blood cell transition in the experimental segment to that in the reference segment) and S ratio (the ratio of S-the effective area of the vascular bed against the total area of the vascular bed-in the experimental segment to that in the reference segment). Rats were divided into group 1, comprising animals that survived for 7 days or more, and group 2, which consisted of animals that died within 4 days.
RESULTS: V (max) ratio and S ratio in group 1 were both significantly higher than those in group 2 (P < 0.01). No death occurred at a V (max) ratio of 0.76 or higher and an S ratio of 0.61 or more, while there were no survivors with a V (max) ratio of 0.54 or less and an S ratio of 0.51 or less.
CONCLUSION: V (max) ratio and S ratio could be used as indices for evaluation of intestinal viability. Copyright 2003 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

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Mesh:

Year:  2003        PMID: 12673749     DOI: 10.1002/bjs.4059

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  4 in total

1.  Predicting the survival of experimental ischaemic small bowel using intraoperative near-infrared fluorescence angiography.

Authors:  A Matsui; J H Winer; R G Laurence; J V Frangioni
Journal:  Br J Surg       Date:  2011-09-27       Impact factor: 6.939

2.  Precision real-time evaluation of bowel perfusion: accuracy of confocal endomicroscopy assessment of stoma in a controlled hemorrhagic shock model.

Authors:  Michele Diana; Eric Noll; Anne-Laure Charles; Pierre Diemunsch; Bernard Geny; Yu-Yin Liu; Francesco Marchegiani; Luigi Schiraldi; Vincent Agnus; Veronique Lindner; Lee Swanström; Bernard Dallemagne; Jacques Marescaux
Journal:  Surg Endosc       Date:  2016-06-20       Impact factor: 4.584

3.  How to assess intestinal viability during surgery: A review of techniques.

Authors:  Linas Urbanavičius; Piet Pattyn; Dirk Van de Putte; Donatas Venskutonis
Journal:  World J Gastrointest Surg       Date:  2011-05-27

4.  Probe-based confocal laser endomicroscopy and fluorescence-based enhanced reality for real-time assessment of intestinal microcirculation in a porcine model of sigmoid ischemia.

Authors:  Michele Diana; Bernard Dallemagne; Hyunsoo Chung; Yoshihiro Nagao; Peter Halvax; Vincent Agnus; Luc Soler; Veronique Lindner; Nicolas Demartines; Pierre Diemunsch; Bernard Geny; Lee Swanström; Jacques Marescaux
Journal:  Surg Endosc       Date:  2014-06-17       Impact factor: 4.584

  4 in total

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