Literature DB >> 12671654

Wnts as morphogens? The view from the wing of Drosophila.

Alfonso Martinez Arias1.   

Abstract

Morphogens are diffusible signalling molecules that pattern cellular fields by setting up differential gene expression in a concentration-dependent manner. Members of the Wnt family of signalling molecules are generally considered to be classical morphogens. However, a close analysis of their activity indicates that they do not fulfil all of the critera that are associated with the classical definition.

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Year:  2003        PMID: 12671654     DOI: 10.1038/nrm1078

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  17 in total

1.  Control of growth and positional information by the graded vestigial expression pattern in the wing of Drosophila melanogaster.

Authors:  L A Baena-Lopez; A García-Bellido
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-01       Impact factor: 11.205

Review 2.  Understanding morphogen gradients: a problem of dispersion and containment.

Authors:  Thomas B Kornberg; Arjun Guha
Journal:  Curr Opin Genet Dev       Date:  2007-07-23       Impact factor: 5.578

3.  Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.

Authors:  Penny Hayward; Keith Brennan; Phil Sanders; Tina Balayo; Ramanuj DasGupta; Norbert Perrimon; Alfonso Martinez Arias
Journal:  Development       Date:  2005-03-16       Impact factor: 6.868

Review 4.  A systematic review on the effects of acrylamide and bisphenol A on the development of Drosophila melanogaster.

Authors:  Swetha Senthil Kumar; Abhinaya Swaminathan; Mohamed M Abdel-Daim; Sahabudeen Sheik Mohideen
Journal:  Mol Biol Rep       Date:  2022-06-26       Impact factor: 2.316

5.  Cell-autonomous, myristyl-independent activity of the Drosophila Wnt/Wingless antagonist Naked cuticle (Nkd).

Authors:  Chih-Chiang Chan; Shu Zhang; Tolga Cagatay; Keith A Wharton
Journal:  Dev Biol       Date:  2007-09-15       Impact factor: 3.582

Review 6.  Wnt proteins in mammary development and cancer.

Authors:  Keith R Brennan; Anthony M C Brown
Journal:  J Mammary Gland Biol Neoplasia       Date:  2004-04       Impact factor: 2.673

7.  Patterning and growth control by membrane-tethered Wingless.

Authors:  Cyrille Alexandre; Alberto Baena-Lopez; Jean-Paul Vincent
Journal:  Nature       Date:  2013-12-25       Impact factor: 49.962

8.  Cell lineage transport: a mechanism for molecular gradient formation.

Authors:  Marta Ibañes; Yasuhiko Kawakami; Diego Rasskin-Gutman; Juan Carlos Izpisúa Belmonte
Journal:  Mol Syst Biol       Date:  2006-10-17       Impact factor: 11.429

9.  Wingless signalling alters the levels, subcellular distribution and dynamics of Armadillo and E-cadherin in third instar larval wing imaginal discs.

Authors:  Ildiko M L Somorjai; Alfonso Martinez-Arias
Journal:  PLoS One       Date:  2008-08-06       Impact factor: 3.240

Review 10.  Theoretical and experimental approaches to understand morphogen gradients.

Authors:  Marta Ibañes; Juan Carlos Izpisúa Belmonte
Journal:  Mol Syst Biol       Date:  2008-03-25       Impact factor: 11.429

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