Literature DB >> 12671584

[Noma in HIV-infected adults].

O Faye1, M Keita, H-T N'diaye, H-D Konare, H Darie, S Keita, A Mahe.   

Abstract

INTRODUCTION: Noma is a necrotic stomatitis, frequent in undernourished children in tropical countries. Its occurrence in adults is extremely rare and has recently been described during AIDS. We report two new cases. OBSERVATIONS: The first patient, a 37 year-old farmer, consulted for a mutilating ulcer of the commissure of the right lip. The second patient, a 25 year-old woman, consulted for an ulcerating and necrotic tumefaction of the left cheek. Anamnesis reconstructed the chronology of the lesions and a cutaneous biopsy revealed non-specific ulcers. The status of health of both patients was poor and they both exhibited positive HIV serology. DISCUSSION: The diagnosis of noma is easy and based on clinical manifestations. The characteristic aspect is that of a mutilating ulcer of the face with conventional progression: tumefaction, followed by ulceration and finally elimination necrosis. This disease predominates in children. Its discovery in adults is a sign of poor prognosis because it may reveal an HIV infection at the AIDS stage.
CONCLUSION: It is important to draw the attention of practitioners on the interest of performing HIV serology when confronted with an adult exhibiting a noma, and to evoke a noma when confronted with a tumefaction of the face rapidly progressing towards necrosis.

Entities:  

Mesh:

Year:  2003        PMID: 12671584

Source DB:  PubMed          Journal:  Ann Dermatol Venereol        ISSN: 0151-9638            Impact factor:   0.777


  2 in total

Review 1.  Oral ranula in an HIV-positive patient: case report and literature review.

Authors:  Andrew Jon Kinshuck; Marianne Schober; George Kokai; Ray Clarke
Journal:  BMJ Case Rep       Date:  2012-07-10

Review 2.  A Review on Noma: A Recent Update.

Authors:  Nipun Ashok; Bassel Tarakji; Shourouk Darwish; Jean C Rodrigues; Mohammad A Altamimi
Journal:  Glob J Health Sci       Date:  2015-07-30
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.