| Literature DB >> 12670653 |
Hea-Young Park Choo1, Suyoung Choi, Chung-Kyu Ryu, Hwa-Jung Kim, In Young Lee, Ae Nim Paeb, Hun Yeong Koh.
Abstract
The 3D-QSAR study of quinolinediones which showed potent inhibitory effect on the acetylcholine induced vasorelaxation of rat aorta with the endothelium was conducted by CoMSIA. The statistical result, cross-validated q(2) (0.741) and r(2) (0.960) values, gave reliability to the prediction of inhibitory activity of this series.Entities:
Mesh：
Substances：
Year: 2003 PMID： 12670653 DOI： 10.1016/s0968-0896(03)00045-2
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641