Literature DB >> 12669867

A novel concept to activate enediynes for DNA cleavage.

Michael Schmittel1, Giampietro Viola, Francesco Dall'Acqua, Guido Morbach.   

Abstract

A novel concept is presented to activate enediynes via a biscumulenic intermediate using photoinduced electron transfer (PET).

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Year:  2003        PMID： 12669867     DOI： 10.1039/b211783e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Identification of the adduct between a 4-Aza-3-ene-1,6-diyne and DNA using electrospray ionization mass spectrometry.

Authors:  Courtney L Sherman; Sarah E Pierce; Jennifer S Brodbelt; Bodin Tuesuwan; Sean M Kerwin
Journal:  J Am Soc Mass Spectrom       Date:  2006-07-26       Impact factor: 3.109

2.  DNA damage-site recognition by lysine conjugates.

Authors:  Boris Breiner; Jörg C Schlatterer; Igor V Alabugin; Serguei V Kovalenko; Nancy L Greenbaum
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-30       Impact factor: 11.205

3.  C-lysine conjugates: pH-controlled light-activated reagents for efficient double-stranded DNA cleavage with implications for cancer therapy.

Authors:  Wang-Yong Yang; Boris Breiner; Serguei V Kovalenko; Chi Ben; Mani Singh; Shauna N LeGrand; Qing-Xiang Amy Sang; Geoffrey F Strouse; John A Copland; Igor V Alabugin
Journal:  J Am Chem Soc       Date:  2009-08-19       Impact factor: 15.419

4.  Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates.

Authors:  Wang-Yong Yang; Samantha A Marrone; Nalisha Minors; Diego A R Zorio; Igor V Alabugin
Journal:  Beilstein J Org Chem       Date:  2011-06-16       Impact factor: 2.883
  4 in total

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