New cerebrosides from the basidiomycete Cortinarius tenuipes.

Five cerebrosides (1-5), including three new ones named cortenuamide A (1), cortenuamide B (2), and cortenuamide C (3), were isolated from the fruiting bodies of the basidiomycete Cortinarius tenuipes. The structures of those compounds were elucidated as (4E,8E)-N-D-2'-hydroxytetracosanoyl-1-O-beta-D-glycopyranosyl-9-methyl-4,8-sphingadienine (1), (4E, 8E)-N-D-2'-hydroxytricosanoyl-1-O-beta-D-glycopyranosyl-9-methyl-4,8 sphingadienine (2), (4E, 8E)-N-D-2'-hydroxydocosanoyl-1-O-beta-D-glycopyranosyl-9-methyl-4,8-sphingadienine (3), (4E, 8E)-N-D-2'-hydroxyoctadecanoyl-1-O-beta-D-glycopyranosyl-9-methyl-4,8-sphingadienine (4), and (4E,8E)-N-D-2'-hydroxypalmitoyl-1-O-beta-D-glycopyranosyl-9-methyl-4,8-sphingadienine (5) by spectral and chemical methods.