AIM: This review is intended to be a critical analysis of selected red-ox methodologies aimed at understanding why the biomarker might be valuable and how it can be measured, highlighting any pitfalls and sample interferences, and describing specific cases of application. DATA SUMMARY: Over recent years, considerable efforts have been made to identify and validate the markers of the oxidative/antioxidant status of the human body. CONCLUSION: Different assays must be applied simultaneously and the related information merged in order to obtain a clearer picture of red-ox status. The relevance of the markers needs to be understood in both pathological and physiological terms: more information is needed about how these markers are regulated in human beings and how they are associated with the diet, because improving health and well-being is as important as preventing the risks of disease itself.
AIM: This review is intended to be a critical analysis of selected red-ox methodologies aimed at understanding why the biomarker might be valuable and how it can be measured, highlighting any pitfalls and sample interferences, and describing specific cases of application. DATA SUMMARY: Over recent years, considerable efforts have been made to identify and validate the markers of the oxidative/antioxidant status of the human body. CONCLUSION: Different assays must be applied simultaneously and the related information merged in order to obtain a clearer picture of red-ox status. The relevance of the markers needs to be understood in both pathological and physiological terms: more information is needed about how these markers are regulated in human beings and how they are associated with the diet, because improving health and well-being is as important as preventing the risks of disease itself.