Literature DB >> 12669512

[Pentylenetetrazole kindling induces caspase-3 activation in rat brain].

T V Pavlova1, A A Iakovlev, M Iu Stepanichev, A M Mendzheritskiĭ, N V Guliaeva.   

Abstract

Pentylenetetrazole kindling (but not a single pentylenetetrazole injection) induced caspase-3 activation in the cerebral cortex, hippocampus, and cerebellum of rats as well as neurodegeneration in the hippocampus. The number of neurons in the CA3 subfield of the hippocampus decreased significantly, whereas no apoptotic nuclei could be detected. The results support a possible non-apoptotic involvement of caspase-3 in brain plasticity.

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Year:  2003        PMID： 12669512

Source DB:  PubMed          Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova        ISSN： 0044-4677            Impact factor:   0.437


  3 in total

1.  Electroconvulsive shock induces neuron death in the mouse hippocampus: correlation of neurodegeneration with convulsive activity.

Authors:  I I Zarubenko; A A Yakovlev; M Yu Stepanichev; N V Gulyaeva
Journal:  Neurosci Behav Physiol       Date:  2005-09

2.  Acquisition of an active avoidance reaction in rats and morphological changes in the hippocampus in pentylenetetrazol kindling.

Authors:  T V Pavlova; M Y Stepanichev; A B Gekht; N V Gulyaeva
Journal:  Neurosci Behav Physiol       Date:  2010-05-14

3.  Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae).

Authors:  Patrick Amoateng; Eric Woode; Samuel B Kombian
Journal:  J Pharm Bioallied Sci       Date:  2012-04
  3 in total

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