Literature DB >> 12669445

[A randomized controlled study on the efficacy of modified sclerotherapy in treating angioma of ear, nose and throat].

Kaiyuan Zhou1, Chuanyu Liang, Keqin Yang, Lihong Wang.   

Abstract

OBJECTIVE: To evaluate the efficacy and security of modified and traditional sclerotherapy in treating angioma in ENT.
METHOD: For the Angioma of derma and hypodermis (naso face, auricles, neck) 56 cases and 82 cases of mucosa and hypomucosa (the cavities of nose, throat and mouth) were randomized divided into 2 groups each.: The 5% Sodium Morrhate + Triamcinolone Acetonide (The Modified Sclerotherapy n = 28, n = 41) and only 5% Sodium Morrhate (Traditional Sclerotherapy n = 28, n = 41) were respectively injected into bodies of Angioma, as one time a week for 2-6 weeks, on average 19 days. RESULT: The rates of cure and effective for Modified and Traditional Sclerotherapies were 84.1%, 65.2% and 91.3%, 85.5% respectively. There is a significant in statistics for effective rates and there is a notable difference in cured rates between the two therapies. It shows that Modified Sclerotherapy has an obvious advantage (P < 0.05). Although the efficacy is similar between the two therapies for angioma of mucosa and hypomucosa, the difference has a significant in efficacy for angioma of derma and hypoderma between the two therapies (P < 0.05) and the side-effects were very slight for Modified Sclerotherapy.
CONCLUSION: There is a more prominent efficacy and security for Modified Sclerotherapy than Traditional Sclerotherapy.

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Year:  2002        PMID: 12669445

Source DB:  PubMed          Journal:  Lin Chuang Er Bi Yan Hou Ke Za Zhi


  2 in total

Review 1.  Interventions for infantile haemangiomas of the skin.

Authors:  Monica Novoa; Eulalia Baselga; Sandra Beltran; Lucia Giraldo; Ali Shahbaz; Hector Pardo-Hernandez; Ingrid Arevalo-Rodriguez
Journal:  Cochrane Database Syst Rev       Date:  2018-04-18

2.  Delivery of sodium morrhuate to hemangioma endothelial cells using immunoliposomes conjugated with anti-VEGFR2/KDR antibody.

Authors:  Xiaoli Li; Xiaoyong Ren; Jianmin Liang; Weijun Ma; Zhenghui Wang; Zhuangqun Yang
Journal:  Int J Nanomedicine       Date:  2017-09-19
  2 in total

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