| Literature DB >> 12669396 |
Shigetaka Kuroki1, Kentaro Iwanaga, Osamu Kato, Koichiro Takahashi, Yoshio Haruta, Yoshinobu Soejima, Koutarou Koyanagi, Tsugio Furukawa, Yoshifumi Soejima, Masaki Nagata, Keiko Naitoh, Yosuke Aoki, Shinichiro Hayashi.
Abstract
A multicenter cooperative study of docetaxel (60 mg/m2) combined with cisplatin (60 mg/m2) was performed in stage III and IV patients with inoperable non-small cell lung cancer from March 1998 to September 1999. Of 37 patients enrolled, 36 patients were eligible. One patient obtained a complete response (CR) and nine patients had a partial response (PR). The overall response rate in 36 patients was 28.6%. The median survival time was 360 days. The response rates of stage III and stage IV patients were 36.8% and 18.7%, respectively. The median survival times of stage III and stage IV patients were 502 days and 286 days, respectively. The major toxicities were grade 3 leukopenia (16.2%), grade 3 neutropenia (32.4%), and grade 4 neutropenia (10.8%).Entities:
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Year: 2003 PMID： 12669396
Source DB: PubMed Journal: Gan To Kagaku Ryoho ISSN： 0385-0684