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Literature DB >> 12668542

Acute hepatitis associated with oral levofloxacin therapy in a hemodialysis patient.

Abstract

Levofloxacin is a fluoroquinolone antibiotic commonly used to treat respiratory, urinary tract, skin and soft-tissue infections. Levofloxacin is generally well tolerated and has fewer reported side effects than other fluoroquinolones. We present a case of levofloxacin-associated severe hepatocellular injury. The hepatitis resolved soon after discontinuation of levofloxacin.

Entities: Chemical Disease Species

Mesh：

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Year: 2003 PMID： 12668542 PMCID： PMC151990

Source DB: PubMed Journal: CMAJ ISSN： 0820-3946 Impact factor: 8.262

11 in total

1. Fatal subfulminant hepatic failure with ofloxacin.

Authors: P González Carro; M L Huidobro; A P Zabala; E M Vicente
Journal: Am J Gastroenterol Date: 2000-06 Impact factor: 10.864

2. Severe ciprofloxacin-induced acute hepatitis.

Authors: M A Contreras; R Luna; J Mulero; J L Andreu
Journal: Eur J Clin Microbiol Infect Dis Date: 2001-06 Impact factor: 3.267

3. Acute fatal hepatitis related to levofloxacin.

Authors: L Spahr; L Rubbia-Brandt; O Marinescu; B Armenian; A Hadengue
Journal: J Hepatol Date: 2001-08 Impact factor: 25.083

4. Possible levofloxacin-induced acute hepatocellular injury in a patient with chronic obstructive lung disease.

Authors: A Karim; S Ahmed; L J Rossoff; R K Siddiqui; H N Steinberg
Journal: Clin Infect Dis Date: 2001-11-09 Impact factor: 9.079

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Authors: S R Norrby
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Authors: J B Kahn
Journal: Chemotherapy Date: 2001 Impact factor: 2.544

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Authors: J Bertino; D Fish
Journal: Clin Ther Date: 2000-07 Impact factor: 3.393

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Authors: N E Henann; M F Zambie
Journal: Pharmacotherapy Date: 2001-12 Impact factor: 4.705

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Authors: B A Lipsky; C A Baker
Journal: Clin Infect Dis Date: 1999-02 Impact factor: 9.079

Review 10. Overview of fluoroquinolone safety.

Authors: J S Wolfson; D C Hooper
Journal: Am J Med Date: 1991-12-30 Impact factor: 4.965

8 in total

1. Acute hepatitis associated with levofloxacin in a patient with renal insufficiency.

Authors: Kelly Airey; Elizabeth Koller
Journal: CMAJ Date: 2003-10-14 Impact factor: 8.262

2. Clinical and histopathologic features of fluoroquinolone-induced liver injury.

Authors: Eric S Orman; Hari S Conjeevaram; Raj Vuppalanchi; James W Freston; James Rochon; David E Kleiner; Paul H Hayashi
Journal: Clin Gastroenterol Hepatol Date: 2011-02-26 Impact factor: 11.382

Review 3. Levofloxacin: a review of its use in the treatment of bacterial infections in the United States.

Authors: Katherine F Croom; Karen L Goa
Journal: Drugs Date: 2003 Impact factor: 9.546

Review 4. Safety profile of the respiratory fluoroquinolone moxifloxacin: comparison with other fluoroquinolones and other antibacterial classes.

Authors: Françoise Van Bambeke; Paul M Tulkens
Journal: Drug Saf Date: 2009 Impact factor: 5.606