Literature DB >> 12668105

A practical synthesis of a (1-->6)-linked beta-D-glucosamine nonasaccharide.

Feng Yang1, Yuguo Du.   

Abstract

A (1-->6)-beta-D-glucosamine nonasaccharide was convergently synthesized using isopropyl thioglycosides as donors. Anomeric acetylated glucosamine derivatives were proved to be good acceptors in the NIS/TMSOTf catalyzed glycosylation. The target nonasaccharide showed a mild antitumor activity against H22 on the preliminary mice tests.

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Year:  2003        PMID： 12668105     DOI： 10.1016/s0008-6215(02)00494-9

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  3 in total

1.  Protecting group-free glycoligation by the desulfurative rearrangement of allylic disulfides as a means of assembly of oligosaccharide mimetics.

Authors:  Venkataraman Subramanian; Myriame Moumé-Pymbock; Tianshun Hu; David Crich
Journal:  J Org Chem       Date:  2011-03-23       Impact factor: 4.354

2.  Synthesis of β-(1→6)-linked N-acetyl-D-glucosamine oligosaccharide substrates and their hydrolysis by Dispersin B.

Authors:  Anikó Fekete; Anikó Borbás; Gyöngyi Gyémánt; Lili Kandra; Erika Fazekas; Narayanan Ramasubbu; Sándor Antus
Journal:  Carbohydr Res       Date:  2011-03-23       Impact factor: 2.104

Review 3.  Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004.

Authors:  David J Harvey
Journal:  Mass Spectrom Rev       Date:  2009 Mar-Apr       Impact factor: 10.946
  3 in total

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