Literature DB >> 12668016

First enantiodivergent Baeyer-Villiger oxidation by recombinant whole-cells expressing two monooxygenases from Brevibacterium.

Marko D Mihovilovic1, Florian Rudroff, Bernhard Müller, Peter Stanetty.   

Abstract

Microbial Baeyer-Villiger oxidations of representative mesomeric ketones with recombinant Escherichia coli cells expressing two monooxygenases from Brevibacterium were investigated. The two enzymes displayed enantiodivergent biotransformations on an array of structurally diverse substrates, allowing access to some key lactone intermediates in natural compound synthesis.

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Year:  2003        PMID： 12668016     DOI： 10.1016/s0960-894x(03)00137-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

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Authors:  Joerg H Schrittwieser; Verena Resch
Journal:  RSC Adv       Date:  2013-08-07       Impact factor: 3.361

2.  First chemo-enzymatic synthesis of the (R)-Taniguchi lactone and substrate profiles of CAMO and OTEMO, two new Baeyer-Villiger monooxygenases.

Authors:  Florian Rudroff; Michael J Fink; Ramana Pydi; Uwe T Bornscheuer; Marko D Mihovilovic
Journal:  Monatsh Chem       Date:  2016-12-21       Impact factor: 1.451

3.  Bio-Catalytic Structural Transformation of Anti-cancer Steroid, Drostanolone Enanthate with Cephalosporium aphidicola and Fusarium lini, and Cytotoxic Potential Evaluation of Its Metabolites against Certain Cancer Cell Lines.

Authors:  M Iqbal Choudhary; Mahwish Siddiqui; Sammer Yousuf; Narjis Fatima; Malik S Ahmad; Hani Choudhry
Journal:  Front Pharmacol       Date:  2017-12-20       Impact factor: 5.810
  3 in total

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