Literature DB >> 12667699

Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines.

Jean Yves Winum1, Jean Luc Bouissière, Isabelle Passagne, Alexandre Evrard, Véronique Montero, Pierre Cuq, Jean Louis Montero.   

Abstract

Two new analogues of Fotemustine have been synthesized and tested on two melanoma cell lines. Compounds 4 and 8 proved to be more potent than the reference compound on A375 cell line which express the MGMT enzyme involved in the chemoresistance of tumoral cells.

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Year:  2003        PMID： 12667699     DOI： 10.1016/s0223-5234(03)00014-x

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  3 in total

1.  tert-Butyl N-[N,N-bis-(2-chloro-ethyl)sulfamo-yl]-N-(2-chloro-ethyl)carbamate.

Authors:  Achour Seridi; Hocine Akkari; Jean-Yves Winum; Patricia Bénard-Rocherullé; Mohamed Abdaoui
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-09-26

2.  Influence of the Expression Level of O6-Alkylguanine-DNA Alkyltransferase on the Formation of DNA Interstrand Crosslinks Induced by Chloroethylnitrosoureas in Cells: A Quantitation Using High-Performance Liquid Chromatography-Mass Spectrometry.

Authors:  Lili Li; Sisi Li; Guohui Sun; Ruizeng Peng; Lijiao Zhao; Rugang Zhong
Journal:  PLoS One       Date:  2015-03-23       Impact factor: 3.240

3.  Synthesis, Spectroscopic Characterization, and In Vitro Antibacterial Evaluation of Novel Functionalized Sulfamidocarbonyloxyphosphonates.

Authors:  Abdeslem Bouzina; Khaoula Bechlem; Hajira Berredjem; Billel Belhani; Imène Becheker; Jacques Lebreton; Marc Le Borgne; Zouhair Bouaziz; Christelle Marminon; Malika Berredjem
Journal:  Molecules       Date:  2018-07-10       Impact factor: 4.411
  3 in total

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