Literature DB >> 12665245

RNA-binding proteins that target the androgen receptor mRNA.

Jackie A Wilce1, Peter J Leedman, Matthew C J Wilce.   

Abstract

Recent efforts to elucidate mechanisms of posttranscriptional gene regulation have resulted in the description of both cis- and trans-acting factors which affect the stability and translational efficiency of specific mRNAs. Here we summarise some of the concepts in this field, with particular attention to recently discovered protein/RNA interactions involving the human androgen receptor mRNA. Such systems are of interest for their potential as targets for the modulation of protein production.

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Year:  2002        PMID: 12665245     DOI: 10.1080/15216540216033

Source DB:  PubMed          Journal:  IUBMB Life        ISSN: 1521-6543            Impact factor:   3.885


  3 in total

1.  Formation of an alphaCP1-KH3 complex with UC-rich RNA.

Authors:  M Sidiqi; J A Wilce; C J Porter; A Barker; P J Leedman; M C J Wilce
Journal:  Eur Biophys J       Date:  2005-03-09       Impact factor: 1.733

Review 2.  Adaptive responses of androgen receptor signaling in castration-resistant prostate cancer.

Authors:  Sven Perner; Marcus V Cronauer; Andres Jan Schrader; Helmut Klocker; Zoran Culig; Aria Baniahmad
Journal:  Oncotarget       Date:  2015-11-03

3.  A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling.

Authors:  Andrea Köhler; Ummühan Demir; Eva Kickstein; Sybille Krauss; Johanna Aigner; Beatriz Aranda-Orgillés; Antonios I Karagiannidis; Clemens Achmüller; Huajie Bu; Andrea Wunderlich; Michal-Ruth Schweiger; Georg Schaefer; Susann Schweiger; Helmut Klocker; Rainer Schneider
Journal:  Mol Cancer       Date:  2014-06-09       Impact factor: 27.401

  3 in total

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