| Literature DB >> 12665035 |
Jie Zhang1, Jang-Zern Tsai, Hong Cao, Yi Chen, James A Will, Vicken R Vorperian, John G Webster.
Abstract
Radio-frequency (RF) cardiac catheter ablation has been very successful for treating some cardiac arrhythmias, however, the success rate for ventricular tachycardias is still not satisfactory. Some existing methods for developing deeper lesions include active cooling of the electrode and modifying the electrode shape. We propose a method of noncontact ablation, to solve this problem. We apply 120 W of power through an 8-mm electrode for a 120-s duration, with distances from 0 to 3 mm between electrode and myocardium, to create lesions in myocardium. We apply flow rates of 1, 3, and 5 L/min to determine their effect. Results show that with an optimal distance from 0.5 to 1.5 mm between electrode and myocardium, we increase lesion depth from 7.5 mm for contact ablation to 9.5 mm for noncontact ablation. For different flow rates, the optimal distance various. The effect of flow rate is not obvious. Higher flow rate does not lead to a deeper lesion.Entities:
Mesh:
Year: 2003 PMID: 12665035 DOI: 10.1109/TBME.2002.807647
Source DB: PubMed Journal: IEEE Trans Biomed Eng ISSN: 0018-9294 Impact factor: 4.538