Literature DB >> 12664783

[Use of peg-intron in combined treatment of chronic liver disease caused by HIV infection].

N I Pomova, I O Ivanikov, V E Siutkin.   

Abstract

The efficiency of treatment of patients with chronic hepatitis type C and liver cirrhosis of HCV etiology with PegIntron in conjunction with Ribavirin made up 73.3% in the group of patients with different HCV genotypes. Due to the development of side effects, it was possible to perform the complete course of treatment only in 30 patients out of 34 (88.2%). Side effects from the side of the central nervous system (irritability, depressive syndrome, sleep disorders), skin (xerodermia, alopecia, seborrhea), and weight loss prevailed against the background of combined treatment with PegIntron and Ribavirin. Upon the completion of treatment, side effects disappeared in 31 patients out of 34 (91.2%) within 1-3 months.

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Year:  2003        PMID: 12664783

Source DB:  PubMed          Journal:  Eksp Klin Gastroenterol        ISSN: 1682-8658


  2 in total

Review 1.  Inflammatory cytokine-associated depression.

Authors:  Francis E Lotrich
Journal:  Brain Res       Date:  2014-07-05       Impact factor: 3.252

2.  Depression following pegylated interferon-alpha: characteristics and vulnerability.

Authors:  Francis E Lotrich; Mordechai Rabinovitz; Patricia Gironda; Bruce G Pollock
Journal:  J Psychosom Res       Date:  2007-08       Impact factor: 3.006

  2 in total

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