Literature DB >> 12663801

Adenovirus dodecahedron allows large multimeric protein transduction in human cells.

P Fender1, G Schoehn, J Foucaud-Gamen, E Gout, A Garcel, E Drouet, J Chroboczek.   

Abstract

Adenovirus dodecahedron is a virus-like particle composed of only two viral proteins of human adenovirus serotype 3 that are responsible for virus attachment and internalization. We show here that this dodecameric particle, devoid of genetic information, efficiently penetrates human cells and can deliver large multimeric proteins such as immunoglobulins.

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Year:  2003        PMID： 12663801      PMCID： PMC152161          DOI： 10.1128/jvi.77.8.4960-4964.2003

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

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Journal:  Curr Opin Mol Ther       Date:  2000-04

3.  Binding of external ligands onto an engineered virus capsid.

Authors:  U Schmidt; R Rudolph; G Böhm
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4.  A peptide carrier for the delivery of biologically active proteins into mammalian cells.

Authors:  M C Morris; J Depollier; J Mery; F Heitz; G Divita
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5.  3PO, a novel nonviral gene delivery system using engineered Ad5 penton proteins.

Authors:  L K Medina-Kauwe; N Kasahara; L Kedes
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Review 6.  Protein transduction: an alternative to genetic intervention?

Authors:  K G Ford; B E Souberbielle; D Darling; F Farzaneh
Journal:  Gene Ther       Date:  2001-01       Impact factor: 5.250

7.  Continuous cultures of fused cells secreting antibody of predefined specificity.

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8.  Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases.

Authors:  Richard Galinier; Evelyne Gout; Hugues Lortat-Jacob; Jonathan Wood; Jadwiga Chroboczek
Journal:  Biochemistry       Date:  2002-12-03       Impact factor: 3.162

9.  Nonviral gene delivery to human breast cancer cells by targeted Ad5 penton proteins.

Authors:  L K Medina-Kauwe; M Maguire; N Kasahara; L Kedes
Journal:  Gene Ther       Date:  2001-12       Impact factor: 5.250

10.  Modified adenovirus penton base protein (UTARVE) as a non-replicating vector for delivery of antisense oligonucleotides with antiviral and/or antineoplastic activity.

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  15 in total

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2.  In vivo delivery of antigens by adenovirus dodecahedron induces cellular and humoral immune responses to elicit antitumor immunity.

Authors:  Ana Villegas-Mendez; Marina I Garin; Estela Pineda-Molina; Eugenia Veratti; Juan A Bueren; Pascal Fender; Jean-Luc Lenormand
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3.  Adenovirus Dodecahedron, a VLP, Can be Purified by Size Exclusion Chromatography Instead of Time-Consuming Sucrose Density Gradient Centrifugation.

Authors:  I Szurgot; M Jedynak; M Podsiadla-Bialoskorska; Jan Piwowarski; E Szolajska; J Chroboczek
Journal:  Mol Biotechnol       Date:  2015-06       Impact factor: 2.695

4.  The adenovirus type 3 dodecahedron's RGD loop comprises an HSPG binding site that influences integrin binding.

Authors:  E Gout; G Schoehn; D Fenel; H Lortat-Jacob; P Fender
Journal:  J Biomed Biotechnol       Date:  2010-03-04

5.  RNA nanotechnology to build a dodecahedral genome of single-stranded RNA virus.

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6.  Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron.

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7.  Cell entry and trafficking of human adenovirus bound to blood factor X is determined by the fiber serotype and not hexon:heparan sulfate interaction.

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8.  A fiber-modified adenoviral vector interacts with immunoevasion molecules of the B7 family at the surface of murine leukemia cells derived from dormant tumors.

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9.  Characterization of a novel type of HIV-1 particle assembly inhibitor using a quantitative luciferase-Vpr packaging-based assay.

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10.  The structural basis for the integrity of adenovirus Ad3 dodecahedron.

Authors:  Ewa Szolajska; Wim P Burmeister; Monika Zochowska; Barbara Nerlo; Igor Andreev; Guy Schoehn; Jean-Pierre Andrieu; Pascal Fender; Antonina Naskalska; Chloe Zubieta; Stephen Cusack; Jadwiga Chroboczek
Journal:  PLoS One       Date:  2012-09-25       Impact factor: 3.240
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