Literature DB >> 12663593

Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use.

Graham P Leese1, Jixian Wang, Janice Broomhall, Paul Kelly, Andrew Marsden, William Morrison, Brian M Frier, Andrew D Morris.   

Abstract

OBJECTIVE: To determine the incidence, predisposing factors, and costs of emergency treatment of severe hypoglycemia in people with type 1 and type 2 diabetes. RESEARCH DESIGN AND METHODS: Over a 12-month period, routinely collected datasets were analyzed in a population of 367,051 people, including 8,655 people with diabetes, to measure the incidence of severe hypoglycemia that required emergency assistance from Ninewells Hospital and Medical School (NHS) personnel including those in primary care, ambulance services, hospital accident and emergency departments, and inpatient care. Associated costs with these episodes were calculated.
RESULTS: A total of 244 episodes of severe hypoglycemia were recorded in 160 patients, comprising 69 (7.1%) people with type 1 diabetes, 66 (7.3%) with type 2 diabetes treated with insulin, and 23 (0.8%) with type 2 diabetes treated with sulfonylurea tablets. Incidence rates were 11.5 and 11.8 events per 100 patient-years for type 1 and type 2 patients treated with insulin, respectively. Age, duration, and socioeconomic status were identified as risk factors for severe hypoglycemia. One in three cases were treated solely by the ambulance service with no other contact from health care professionals. The total estimated cost of emergency treatment of severe hypoglycemia was </= pound 92,078 in one year.
CONCLUSIONS: Hypoglycemia requiring emergency assistance from health service personnel is as common in people with type 2 diabetes treated with insulin as in people with type 1 diabetes. It is associated with considerable NHS resource use that has a significant economic and personal cost.

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Year:  2003        PMID: 12663593     DOI: 10.2337/diacare.26.4.1176

Source DB:  PubMed          Journal:  Diabetes Care        ISSN: 0149-5992            Impact factor:   19.112


  162 in total

1.  Population-based study of severe hypoglycemia requiring emergency medical service assistance reveals unique findings.

Authors:  Ajay K Parsaik; Rickey E Carter; Vishwanath Pattan; Lucas A Myers; Hamit Kumar; Steven A Smith; Christopher S Russi; James A Levine; Ananda Basu; Yogish C Kudva
Journal:  J Diabetes Sci Technol       Date:  2012-01-01

Review 2.  [Hypoglycemia, classification, therapy and preventable errors].

Authors:  R Lobmann; H Lehnert
Journal:  Internist (Berl)       Date:  2003-10       Impact factor: 0.743

Review 3.  Treatment of type 2 diabetes in the elderly.

Authors:  Medha N Munshi; Megumi Maguchi; Alissa R Segal
Journal:  Curr Diab Rep       Date:  2012-06       Impact factor: 4.810

4.  Day and night glycaemic control with a bionic pancreas versus conventional insulin pump therapy in preadolescent children with type 1 diabetes: a randomised crossover trial.

Authors:  Steven J Russell; Mallory A Hillard; Courtney Balliro; Kendra L Magyar; Rajendranath Selagamsetty; Manasi Sinha; Kerry Grennan; Debbie Mondesir; Laya Ekhlaspour; Hui Zheng; Edward R Damiano; Firas H El-Khatib
Journal:  Lancet Diabetes Endocrinol       Date:  2016-02-03       Impact factor: 32.069

5.  A Review of Continuous Glucose Monitoring Data Interpretation in the Age of Automated Insulin Delivery.

Authors:  Laya Ekhlaspour; Ideen Tabatabai; Bruce Buckingham
Journal:  J Diabetes Sci Technol       Date:  2019-05-26

6.  [Hypoglycemia despite hyperglycemia. Is a cerebral glucose deficiency possible even with raised blood sugar levels?].

Authors:  G Erdös; R Lobmann; B Wolcke; C Werner
Journal:  Anaesthesist       Date:  2005-07       Impact factor: 1.041

Review 7.  Reporting Severe Hypoglycemia in Type 1 Diabetes: Facts and Pitfalls.

Authors:  Ulrik Pedersen-Bjergaard; Birger Thorsteinsson
Journal:  Curr Diab Rep       Date:  2017-10-28       Impact factor: 4.810

8.  Low socioeconomic status is associated with increased risk for hypoglycemia in diabetes patients: the Diabetes Study of Northern California (DISTANCE).

Authors:  Seth A Berkowitz; Andrew J Karter; Courtney R Lyles; Jennifer Y Liu; Dean Schillinger; Nancy E Adler; Howard H Moffet; Urmimala Sarkar
Journal:  J Health Care Poor Underserved       Date:  2014-05

9.  Acidosis mediates recurrent hypoglycemia-induced increase in ischemic brain injury in treated diabetic rats.

Authors:  Ashish K Rehni; Vibha Shukla; Miguel A Perez-Pinzon; Kunjan R Dave
Journal:  Neuropharmacology       Date:  2018-03-15       Impact factor: 5.250

10.  Outpatient glycemic control with a bionic pancreas in type 1 diabetes.

Authors:  Steven J Russell; Firas H El-Khatib; Manasi Sinha; Kendra L Magyar; Katherine McKeon; Laura G Goergen; Courtney Balliro; Mallory A Hillard; David M Nathan; Edward R Damiano
Journal:  N Engl J Med       Date:  2014-06-15       Impact factor: 91.245

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