Literature DB >> 1266215

Preimplantational ectogenesis. Science and speculation concerning in vitro fertilization and related procedures.

L E Karp, R P Donahue.   

Abstract

In recent years, technical advances have made preimplantational ectogenesis (in vitro maturation, fertilization and early embryonic development) more than a theoretical concept. Such procedures hold great promise in medical research. However, despite our newly-acquired skills in tissue culture and microsurgical manipulation, and contrary to many sensational articles in the lay press, it is not likely that preimplantational ectogenesis will soon attain wide clinical use in humans. Adverse societal attitudes, based largely upon moral and ethical dilemmas, will probably combine with still-unresolved technical difficulties to restrict the clinical applications.

Entities:  

Mesh:

Year:  1976        PMID: 1266215      PMCID: PMC1130041     

Source DB:  PubMed          Journal:  West J Med        ISSN: 0093-0415


  82 in total

1.  A QUANTITATIVE AND CYTOLOGICAL STUDY OF GERM CELLS IN HUMAN OVARIES.

Authors:  T G BAKER
Journal:  Proc R Soc Lond B Biol Sci       Date:  1963-10-22

2.  A METHOD FOR IN VITRO CULTIVATION OF MOUSE OVA FROM TWO-CELL TO BLASTOCYST.

Authors:  R L BRINSTER
Journal:  Exp Cell Res       Date:  1963-10       Impact factor: 3.905

3.  STUDIES ON THE DEVELOPMENT OF MOUSE EMBRYOS IN VITRO. II. THE EFFECT OF ENERGY SOURCE.

Authors:  R L BRINSTER
Journal:  J Exp Zool       Date:  1965-02

4.  Culture of tubal mouse ova.

Authors:  W K WHITTEN
Journal:  Nature       Date:  1956-01-14       Impact factor: 49.962

5.  Sperm penetration of rat eggs in vitro after dissolution of zona pellucida by chymotrypsin.

Authors:  Y Toyoda; M C Chang
Journal:  Nature       Date:  1968-11-09       Impact factor: 49.962

6.  Development of cortical granules and the cortical reaction in rat and hamster eggs.

Authors:  D Szollosi
Journal:  Anat Rec       Date:  1967-12

7.  Mouse blastocysts grown in vivo and in vitro: carbon dioxide production and trophoblast outgrowth.

Authors:  T M Menke; A McLaren
Journal:  J Reprod Fertil       Date:  1970-10

8.  Follicular cell support of oocyte maturation: production of pyruvate in vitro.

Authors:  R P Donahue; S Stern
Journal:  J Reprod Fertil       Date:  1968-11

9.  Development of eight-cell mouse embryos in vitro.

Authors:  R L Brinster; J L Thomson
Journal:  Exp Cell Res       Date:  1966-05       Impact factor: 3.905

10.  Human oocytes: maturation in chemically defined media.

Authors:  J F Kennedy; R P Donahue
Journal:  Science       Date:  1969-06-13       Impact factor: 47.728

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