Literature DB >> 12662094

Chemical constituents of Calophyllum brasiliense. 2. Structure of three new coumarins and cancer chemopreventive activity of 4-substituted coumarins.

Chihiro Ito1, Masataka Itoigawa, Yoshitaka Mishina, Valdir Cechinel Filho, Fumio Enjo, Harukuni Tokuda, Hoyoku Nishino, Hiroshi Furukawa.   

Abstract

Continuing our search for cancer chemopreventive agents from natural sources, we examined constituents of the stem bark of Calophyllum brasiliense. Three new 4-substituted coumarins named brasimarins A (2), B (3), and C (4) were isolated and characterized, along with 11 known coumarins belonging to the calanolides or inophyllums. We also discuss the inhibitory effects of these coumarins on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells.

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Year:  2003        PMID： 12662094     DOI： 10.1021/np0203640

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  Design, synthesis and experimental validation of novel potential chemopreventive agents using random forest and support vector machine binary classifiers.

Authors:  Brienne Sprague; Qian Shi; Marlene T Kim; Liying Zhang; Alexander Sedykh; Eiichiro Ichiishi; Harukuni Tokuda; Kuo-Hsiung Lee; Hao Zhu
Journal:  J Comput Aided Mol Des       Date:  2014-05-20       Impact factor: 3.686

2.  Migratory decarboxylative coupling of coumarins: synthetic and mechanistic aspects.

Authors:  Ranjan Jana; James J Partridge; Jon A Tunge
Journal:  Angew Chem Int Ed Engl       Date:  2011-04-19       Impact factor: 15.336

3.  Antileishmanial activity of crude extract and coumarin from Calophyllum brasiliense leaves against Leishmania amazonensis.

Authors:  Mislaine Adriana Brenzan; Celso Vataru Nakamura; Benedito Prado Dias Filho; Tânia Ueda-Nakamura; Maria Claudia M Young; Diógenes Aparício Garcia Cortez
Journal:  Parasitol Res       Date:  2007-05-05       Impact factor: 2.289

4.  Palladium-catalyzed, pyrrolidine-mediated arylmethylation of ketones and aldehydes with coumarinyl(methyl) acetates.

Authors:  Kalicharan Cattopadhyay; Antonio Recio; Jon A Tunge
Journal:  Org Biomol Chem       Date:  2012-07-25       Impact factor: 3.876

5.  BF3·Et2O Catalysed 4-Aryl-3-phenyl-benzopyrones, Pro-SERMs, and Their Characterization.

Authors:  Ambika Srivastava; Pooja Singh; Rajesh Kumar
Journal:  Adv Pharmacol Sci       Date:  2015-09-01

6.  Soulamarin, a new coumarin from stem bark of Calophyllum soulattri.

Authors:  Gwendoline Cheng Lian Ee; Siau Hui Mah; Soek Sin Teh; Mawardi Rahmani; Rusea Go; Yun Hin Taufiq-Yap
Journal:  Molecules       Date:  2011-11-23       Impact factor: 4.411

Review 7.  Chemical constituents of the plants of the genus Calophyllum.

Authors:  Xiao-Hui Su; Man-Li Zhang; Li-Geng Li; Chang-Hong Huo; Yu-Cheng Gu; Qing-Wen Shi
Journal:  Chem Biodivers       Date:  2008-12       Impact factor: 2.408

8.  Improving the Antioxidant Properties of Calophyllum inophyllum Seed Oil from French Polynesia: Development and Biological Applications of Resinous Ethanol-Soluble Extracts.

Authors:  Mathieu Cassien; Anne Mercier; Sophie Thétiot-Laurent; Marcel Culcasi; Emilie Ricquebourg; Alice Asteian; Gaëtan Herbette; Jean-Pierre Bianchini; Phila Raharivelomanana; Sylvia Pietri
Journal:  Antioxidants (Basel)       Date:  2021-01-30

Review 9.  Naturally Occurring Calanolides: Occurrence, Biosynthesis, and Pharmacological Properties Including Therapeutic Potential.

Authors:  Lutfun Nahar; Anupam Das Talukdar; Deepa Nath; Sushmita Nath; Aman Mehan; Fyaz M D Ismail; Satyajit D Sarker
Journal:  Molecules       Date:  2020-10-28       Impact factor: 4.411
  9 in total

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