Literature DB >> 12662030

Study of the addition of Grignard reagents to 2-aryl-3H-indol-3-ones.

Yahua Liu1, William W McWhorter.   

Abstract

Grignard reagents are added to the carbonyl group of 2-aryl-3H-indol-3-ones to generate 3-alkyl(or phenyl)-2-aryl-3H-indol-3-ols, which are in turn rearranged to yield 2-alkyl(or phenyl)-2-aryl-1,2-dihydro-3H-indol-3-ones.

Entities:  

Year:  2003        PMID： 12662030     DOI： 10.1021/jo020715f

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  5 in total

1.  Oxidative Coupling of 3-Oxindoles with Indoles and Arenes.

Authors:  Houng Kang; Adriana L Jemison; Erin Nigro; Marisa C Kozlowski
Journal:  ChemSusChem       Date:  2019-05-27       Impact factor: 8.928

2.  Chemoselective and enantioselective oxidation of indoles employing aspartyl peptide catalysts.

Authors:  Filip Kolundzic; Mohammad N Noshi; Meiliana Tjandra; Mohammad Movassaghi; Scott J Miller
Journal:  J Am Chem Soc       Date:  2011-05-23       Impact factor: 15.419

3.  Novel base-initiated cascade reactions of hemiindigos to produce dipolar γ-carbolines and indole-fused pentacycles.

Authors:  V S Velezheva; O L Babii; A A Khodak; E A Alekseeva; Yu V Nelyubina; I A Godovikov; A S Peregudov; K B Majorov; B V Nikonenko
Journal:  RSC Adv       Date:  2019-12-13       Impact factor: 4.036

4.  Synthesis of C2-tetrasubstituted indolin-3-ones via Cu-catalyzed oxidative dimerization of 2-aryl indoles and cross-addition with indoles.

Authors:  Anoop Singh; Satheeshvarma Vanaparthi; Sachin Choudhary; Rangan Krishnan; Indresh Kumar
Journal:  RSC Adv       Date:  2019-08-02       Impact factor: 3.361

5.  Catalytic asymmetric α-Iminol rearrangement: new chiral platforms.

Authors:  Xin Zhang; Richard J Staples; Arnold L Rheingold; William D Wulff
Journal:  J Am Chem Soc       Date:  2014-09-23       Impact factor: 15.419
  5 in total

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