Literature DB >> 12660036

Molecular cytogenetic analysis of a pleuropulmonary blastoma.

Bo Hong1, Zhong Chen, Cheryl M Coffin, Richard Lemons, Bonnie Issa, Arthur Brothman, Holly Zhou.   

Abstract

We report a case of pleuropulmonary blastoma with complex cytogenetic abnormalities, including trisomy 2, trisomy 8, dup(7), der(10) t(8; 10)(q13; q22), add(17), and double minutes (dmin). Fluorescence in situ hybridization FISH analysis demonstrated TP53 deletion and amplification of MYCN; the latter has not been reported in PPB.

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Year:  2003        PMID: 12660036     DOI: 10.1016/s0165-4608(02)00731-8

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  3 in total

Review 1.  Double minutes, cytogenetic equivalents of gene amplification, in human neoplasia - a review.

Authors:  Erich Gebhart
Journal:  Clin Transl Oncol       Date:  2005-12       Impact factor: 3.405

Review 2.  Rhabdoid Tumor Predisposition Syndrome and Pleuropulmonary Blastoma Syndrome.

Authors:  Valerie A Fitzhugh
Journal:  J Pediatr Genet       Date:  2016-03-11

3.  Hidden chromosomal abnormalities in pleuropulmonary blastomas identified by multiplex FISH.

Authors:  Benoit Quilichini; Nicolas Andre; Corinne Bouvier; Marie-Anne Chrestian; Angelique Rome; Dominique Intagliata; Carole Coze; Gabriel Lena; Helene Zattara
Journal:  BMC Cancer       Date:  2006-01-05       Impact factor: 4.430

  3 in total

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