| Literature DB >> 12659855 |
S P Rozhkov1, A S Goryunov, G A Sukhanova, A G Borisova, N N Rozhkova, G V Andrievsky.
Abstract
Physicochemical effects of hydrated C(60) fullerenes (HyFn) on serum albumin molecules were studied using ESR spin labeling and differential scanning microcalorimetry. Molecular-colloidal solution of hydrated C(60) fullerenes and their small spherical fractal clusters in water (C(60)FWS), was shown to stabilize protein hydration, and decrease specific surface energy in water-protein matrix in salt solutions. The mechanism of HyFn interaction with protein is discussed in terms of HyFn induced formation of protein clusters and phase transition of hydration water.Entities:
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Year: 2003 PMID： 12659855 DOI： 10.1016/s0006-291x(03)00392-9
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575