Literature DB >> 12659745

Solution-phase synthesis of combinatorial libraries designed to modulate protein-protein or protein-DNA interactions.

Dale L Boger1.   

Abstract

A short personal perspective on the development of an approach to the solution-phase synthesis of combinatorial libraries for modulating cellular signaling by inhibiting, promoting, or mimicking protein-protein or protein-DNA interactions is provided.

Mesh：

Substances：

Year:  2003        PMID： 12659745     DOI： 10.1016/s0968-0896(03)00031-2

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  7 in total

1.  An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.

Authors:  Lisa M Eubanks; Mark S Hixon; Wei Jin; Sukwon Hong; Colin M Clancy; William H Tepp; Michael R Baldwin; Carl J Malizio; Michael C Goodnough; Joseph T Barbieri; Eric A Johnson; Dale L Boger; Tobin J Dickerson; Kim D Janda
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-09       Impact factor: 11.205

2.  Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.

Authors:  Landon R Whitby; Yoshio Ando; Vincent Setola; Peter K Vogt; Bryan L Roth; Dale L Boger
Journal:  J Am Chem Soc       Date:  2011-06-15       Impact factor: 15.419

3.  Small molecule peptidomimetic inhibitors of importin α/β mediated nuclear transport.

Authors:  Géza Ambrus; Landon R Whitby; Eric L Singer; Oleg Trott; Euna Choi; Arthur J Olson; Dale L Boger; Larry Gerace
Journal:  Bioorg Med Chem       Date:  2010-08-21       Impact factor: 3.641

4.  Structural basis of disease-causing mutations in hepatocyte nuclear factor 1beta.

Authors:  Peng Lu; Geun Bae Rha; Young-In Chi
Journal:  Biochemistry       Date:  2007-10-09       Impact factor: 3.162

5.  Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions.

Authors:  Alex Shaginian; Landon R Whitby; Sukwon Hong; Inkyu Hwang; Bilal Farooqi; Mark Searcey; Jiandong Chen; Peter K Vogt; Dale L Boger
Journal:  J Am Chem Soc       Date:  2009-04-22       Impact factor: 15.419

Review 6.  Transcription and replication mechanisms of Bunyaviridae and Arenaviridae L proteins.

Authors:  François Ferron; Friedemann Weber; Juan Carlos de la Torre; Juan Reguera
Journal:  Virus Res       Date:  2017-01-27       Impact factor: 3.303

Review 7.  Reverse genetics approaches to combat pathogenic arenaviruses.

Authors:  Juan C de la Torre
Journal:  Antiviral Res       Date:  2008-09-07       Impact factor: 5.970
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.