| Literature DB >> 12659739 |
Martin Hubálek1, Lenka Hernychová, Jana Havlasová, Irena Kasalová, Vera Neubauerová, Jirí Stulík, Ales Macela, Margaretha Lundqvist, Pär Larsson.
Abstract
The accessibility of the partial genome sequence of Francisella tularensis strain Schu 4 was the starting point for a comprehensive proteome analysis of the intracellular pathogen F. tularensis. The main goal of this study is identification of protein candidates of value for the development of diagnostics, therapeutics and vaccines. In this review, the current status of 2-DE F. tularensis database building, approaches used for identification of biologically important subsets of F. tularensis proteins, and functional and topological assignments of identified proteins using various prediction programs and database homology searches are presented. Copyright 2002 Elsevier Science B.V.Entities:
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Year: 2003 PMID： 12659739 DOI： 10.1016/s1570-0232(02)00730-4
Source DB: PubMed Journal: J Chromatogr B Analyt Technol Biomed Life Sci ISSN： 1570-0232 Impact factor: 3.205