Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Facile oxidation of aldehydes to acids and esters with Oxone.

Literature DB >> 12659566

Facile oxidation of aldehydes to acids and esters with Oxone.

Benjamin R Travis¹, Meenakshi Sivakumar, G Olatunji Hollist, Babak Borhan.

Abstract

[reaction: see text] A highly efficient, mild, and simple protocol is presented for the oxidation of aldehydes to carboxylic acids utilizing Oxone as the sole oxidant. Direct conversion of aldehydes in alcoholic solvents to their corresponding ester products is also reported. These reactions may prove to be valuable alternatives to traditional metal-mediated oxidations.

Entities: Chemical

Year: 2003 PMID： 12659566 DOI： 10.1021/ol0340078

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

Keyword Cloud
Cited

25 in total

1. Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability.

Authors: Graham R Lawton; Hantamalala Ralay Ranaivo; Laura K Chico; Haitao Ji; Fengtian Xue; Pavel Martásek; Linda J Roman; D Martin Watterson; Richard B Silverman
Journal: Bioorg Med Chem Date: 2009-02-14 Impact factor: 3.641

2. A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids.

Authors: Tanja Knaus; Vasilis Tseliou; Luke D Humphreys; Nigel S Scrutton; Francesco G Mutti
Journal: Green Chem Date: 2018-07-10 Impact factor: 10.182

3. A Sequential Cycloaddition Strategy for the Synthesis of Alsmaphorazine B Traces a Path Through a Family of Alstonia Alkaloids.

Authors: Allen Y Hong; Christopher D Vanderwal
Journal: Tetrahedron Date: 2016-11-03 Impact factor: 2.457

4. Copper-catalyzed enantioselective allylic substitution with readily accessible carbonyl- and acetal-containing vinylboron reagents.

Authors: Fang Gao; James L Carr; Amir H Hoveyda
Journal: Angew Chem Int Ed Engl Date: 2012-05-25 Impact factor: 15.336

5. Addressing Structural Flexibility at the A-Ring on Salvinorin A: Discovery of a Potent Kappa-Opioid Agonist with Enhanced Metabolic Stability.

Authors: Alexander M Sherwood; Rachel Saylor Crowley; Kelly F Paton; Andrew Biggerstaff; Benjamin Neuenswander; Victor W Day; Bronwyn M Kivell; Thomas E Prisinzano
Journal: J Med Chem Date: 2017-04-19 Impact factor: 7.446

Facile oxidation of aldehydes to acids and esters with Oxone.

1. Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability.

2. A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids.

3. A Sequential Cycloaddition Strategy for the Synthesis of Alsmaphorazine B Traces a Path Through a Family of Alstonia Alkaloids.

4. Copper-catalyzed enantioselective allylic substitution with readily accessible carbonyl- and acetal-containing vinylboron reagents.

5. Addressing Structural Flexibility at the A-Ring on Salvinorin A: Discovery of a Potent Kappa-Opioid Agonist with Enhanced Metabolic Stability.

6. Photocatalytic C-H Activation and Oxidative Esterification Using Pd@g-C₃N₄.

7. Pd-catalyzed aldehyde to ester conversion: a hydrogen transfer approach.

8. Synthesis of (R)-2-(benzyloxy)-tetrahydro-5,5-dimethylfuran by a new oxidative rearrangement.

9. Baeyer-Villiger Rearrangement of a Substituted Pyrrole by Oxone.

10. Oxidative cyclization of alkenols with oxone using a miniflow reactor.