Literature DB >> 12657266

[3H]-(R)-NPTS, a radioligand for the type 1 glycine transporter.

John A Lowe1, Susan E Drozda, Katherine Fisher, Christine Strick, Lorraine Lebel, Christopher Schmidt, Donna Hiller, Kathleen S Zandi.   

Abstract

The synthesis of NPTS, 6, a potent inhibitor of the type 1 glycine transporter (GlyT1) is described, as well as preparation of 6 in optically active and tritiated form for use as a radioligand for affinity displacement assay of GlyT1.

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Year:  2003        PMID: 12657266     DOI: 10.1016/s0960-894x(03)00126-4

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Pharmacological characterization of [³H]CHIBA-3007 binding to glycine transporter 1 in the rat brain.

Authors:  Jichun Zhang; Jin Wu; Jun Toyohara; Yuko Fujita; Hongxian Chen; Kenji Hashimoto
Journal:  PLoS One       Date:  2011-06-23       Impact factor: 3.240

  1 in total

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