| Literature DB >> 12657264 |
Putta Mallikarjuna Reddy1, Thomas C Bruice.
Abstract
Positively charged DNG oligonucleotide mixed sequences containing A/T bases were prepared by solid-phase synthesis. Synthesis proceeds in 3'-->5' direction and involves coupling of 3'-Fmoc protected thiourea in the presence of HgCl(2)/TEA with the corresponding 5'-amine of the growing oligo chain. DNG binding characteristics with complementary DNA and with itself have been evaluated.Entities:
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Year: 2003 PMID： 12657264 DOI： 10.1016/s0960-894x(03)00119-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823