| Literature DB >> 12657257 |
Suppamit Dettrakul1, Prasat Kittakoop, Masahiko Isaka, Sombat Nopichai, Chotika Suyarnsestakorn, Morakot Tanticharoen, Yodhathai Thebtaranonth.
Abstract
Two new pimarane diterpenes, diaportheins A (1) and B (2), were isolated from a culture broth of the fungus Diaporthe sp. BCC 6140. Diaporthein B (2) strongly inhibited the growth of Mycobacterium tuberculosis with the MIC value of 3.1 microg/mL, while diaporthein A (1) showed only mild activity (MIC value of 200 microg/mL).Entities:
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Year: 2003 PMID: 12657257 DOI: 10.1016/s0960-894x(03)00111-2
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823