Literature DB >> 12657234

Radiofrequency ablation extends the scope of surgery in colorectal liver metastases.

A Oshowo1, A R Gillams, W R Lees, I Taylor.   

Abstract

AIMS: To assess outcome in patients treated by a multidisciplinary team, with a combination of liver resection and RF ablation.
METHODS: Sixteen unselected patients (f=9; m=7) with colorectal liver metastases who were not suitable for surgery alone, were treated as follows: six had RF ablation at open laparotomy, three patients had synchronous ablation and resection while seven patients had RF ablation after liver resection. Standard liver resection techniques were used. RF was performed using internally cooled, single or cluster electrodes with a high power (200 W) generator. All patients were followed with regular contrast enhanced CT and survival noted.
RESULTS: A total of 27 tumours with diameters 1.2-10 cm were treated. Two minor complications were recorded. 2/6 (33%) who had intraoperative RF had incomplete ablation due to large tumour size (6 and 10 cm respectively). Further RF ablation sessions were carried out successfully. 11/16 (69%) are alive at 2 years of whom 7 (44%) have no evidence of residual or recurrent liver disease.
CONCLUSION: In our study, RF ablation extends the therapeutic envelope, is an effective local treatment of liver metastases and improves life expectancy.

Entities:  

Mesh:

Year:  2003        PMID: 12657234     DOI: 10.1053/ejso.2002.1419

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  10 in total

1.  [Nonoperative ablation for liver metastases. Possibilities and limitations as a curative treatment].

Authors:  C-T Germer; H J Buhr; C Isbert
Journal:  Chirurg       Date:  2005-06       Impact factor: 0.955

2.  Guidelines for resection of colorectal cancer liver metastases.

Authors:  O J Garden; M Rees; G J Poston; D Mirza; M Saunders; J Ledermann; J N Primrose; R W Parks
Journal:  Gut       Date:  2006-08       Impact factor: 23.059

Review 3.  Liver-directed treatments for metastatic colorectal cancer.

Authors:  Michael A Choti
Journal:  Curr Treat Options Oncol       Date:  2014-09

4.  Totally laparoscopic strategies for the management of colorectal cancer with synchronous liver metastasis.

Authors:  Francesco M Polignano; Aaron J Quyn; Pandanaboyana Sanjay; Nikola A Henderson; Iain S Tait
Journal:  Surg Endosc       Date:  2012-03-22       Impact factor: 4.584

5.  Curative in situ ablation of colorectal liver metastases-experimental and clinical implementation.

Authors:  Christoph Isbert; Heinz J Buhr; Joerg-Peter Ritz; W Hohenberger; Christoph-T Germer
Journal:  Int J Colorectal Dis       Date:  2006-11-28       Impact factor: 2.571

6.  Open surgical is superior to percutaneous access for radiofrequency ablation of hepatic metastases.

Authors:  Robert M Eisele; Ulf Neumann; Peter Neuhaus; Guido Schumacher
Journal:  World J Surg       Date:  2009-04       Impact factor: 3.352

Review 7.  Hepatic metastasis from colorectal cancer.

Authors:  Alfred Wei Chieh Kow
Journal:  J Gastrointest Oncol       Date:  2019-12

8.  Thermal ablation of colorectal liver metastases: a position paper by an international panel of ablation experts, The Interventional Oncology Sans Frontières meeting 2013.

Authors:  Alice Gillams; Nahum Goldberg; Muneeb Ahmed; Reto Bale; David Breen; Matthew Callstrom; Min Hua Chen; Byung Ihn Choi; Thierry de Baere; Damian Dupuy; Afshin Gangi; Debra Gervais; Thomas Helmberger; Ernst-Michael Jung; Fred Lee; Riccardo Lencioni; Ping Liang; Tito Livraghi; David Lu; Franca Meloni; Philippe Pereira; Fabio Piscaglia; Hyunchul Rhim; Riad Salem; Constantinos Sofocleous; Stephen B Solomon; Michael Soulen; Masatoshi Tanaka; Thomas Vogl; Brad Wood; Luigi Solbiati
Journal:  Eur Radiol       Date:  2015-05-22       Impact factor: 5.315

9.  Radiofrequency ablation versus resection for technically resectable colorectal liver metastasis: a propensity score analysis.

Authors:  Li-Jun Wang; Zhong-Yi Zhang; Xiao-Luan Yan; Wei Yang; Kun Yan; Bao-Cai Xing
Journal:  World J Surg Oncol       Date:  2018-10-15       Impact factor: 2.754

10.  Integrating interventional oncology in the treatment of liver tumors.

Authors:  D Putzer; P Schullian; E Braunwarth; M Fodor; F Primavesi; B Cardini; T Resch; R Oberhuber; M Maglione; C Margreiter; S Schneeberger; S Stättner; D Öfner-Velano; W Jaschke; R J Bale
Journal:  Eur Surg       Date:  2018-04-13       Impact factor: 0.953

  10 in total

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