| Literature DB >> 12655011 |
Gertrud Mannhaupt1, Corinna Montrone, Dirk Haase, H Werner Mewes, Verena Aign, Jörg D Hoheisel, Berthold Fartmann, Gerald Nyakatura, Frank Kempken, Josef Maier, Ulrich Schulte.
Abstract
The German Neurospora Genome Project has assembled sequences from ordered cosmid and BAC clones of linkage groups II and V of the genome of Neurospora crassa in 13 and 12 contigs, respectively. Including additional sequences located on other linkage groups a total of 12 Mb were subjected to a manual gene extraction and annotation process. The genome comprises a small number of repetitive elements, a low degree of segmental duplications and very few paralogous genes. The analysis of the 3218 identified open reading frames provides a first overview of the protein equipment of a filamentous fungus. Significantly, N.crassa possesses a large variety of metabolic enzymes including a substantial number of enzymes involved in the degradation of complex substrates as well as secondary metabolism. While several of these enzymes are specific for filamentous fungi many are shared exclusively with prokaryotes.Entities:
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Year: 2003 PMID： 12655011 PMCID： PMC152809 DOI： 10.1093/nar/gkg293
Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971