Literature DB >> 12654859

Bidirectional concentration-dependent effects of tumor necrosis factor alpha in Shigella dysenteriae-related seizures.

Yael Yuhas1, Abraham Weizman, Shai Ashkenazi.   

Abstract

We have previously demonstrated that pretreatment of mice with Shigella dysenteriae sonicate enhanced their susceptibility to pentylenetetrazole-induced seizures and that tumor necrosis factor alpha (TNF-alpha) was proconvulsive in this respect. The present study shows that TNF-alpha, at high concentrations, may also exert a suppressive effect on Shigella-mediated seizures. This implies that high levels of TNF-alpha may play a protective role in neurologic complications of S. dysenteriae infection.

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Year:  2003        PMID: 12654859      PMCID: PMC152059          DOI: 10.1128/IAI.71.4.2288-2291.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  28 in total

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Journal:  Infect Immun       Date:  1999-12       Impact factor: 3.441

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Journal:  Infect Immun       Date:  1991-11       Impact factor: 3.441

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Journal:  Infect Immun       Date:  1989-11       Impact factor: 3.441

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6.  Risk factors and outcome of Shigella encephalopathy in Bangladeshi children.

Authors:  Farzana Afroze; Tahmeed Ahmed; Monira Sarmin; Abu Smsb Shahid; K M Shahunja; Lubaba Shahrin; Mohammod Jobayer Chisti
Journal:  PLoS Negl Trop Dis       Date:  2017-04-28

7.  Neurochemical effects of sleep deprivation in the hippocampus of the pilocarpine-induced rat model of epilepsy.

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Journal:  Iran J Basic Med Sci       Date:  2021-01       Impact factor: 2.699

8.  Changes in Neuronal Excitability by Activated Microglia: Differential Na(+) Current Upregulation in Pyramid-Shaped and Bipolar Neurons by TNF-α and IL-18.

Authors:  Lars Klapal; Birte A Igelhorst; Irmgard D Dietzel-Meyer
Journal:  Front Neurol       Date:  2016-03-30       Impact factor: 4.003

9.  A Prospective Study of Novel Therapeutic Targets Interleukin 6, Tumor Necrosis Factor α, and Interferon γ as Predictive Biomarkers for the Development of Posttraumatic Epilepsy.

Authors:  Ajay Choudhary; Rahul Varshney; Ashok Kumar; Kaviraj Kaushik
Journal:  World Neurosurg X       Date:  2021-05-28

10.  Convulsions in children hospitalized for acute gastroenteritis.

Authors:  Moti Iflah; Eias Kassem; Uri Rubinstein; Sophy Goren; Moshe Ephros; Dani Cohen; Khitam Muhsen
Journal:  Sci Rep       Date:  2021-08-05       Impact factor: 4.379

  10 in total

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