Literature DB >> 12653865

Detection of HHV-8 sequences and antigens in a MALT lymphoma associated with Sjögren's syndrome.

Jens Peter Klussmann1, Mathias Wagner, Orlando Guntinas-Lichius, Andreas Müller.   

Abstract

We describe the case of a bilateral parotid mucosa-associated lymphoid tissue (MALT) lymphoma associated with 2 years history of Sjögren's syndrome (SS), which was linked to human herpes virus 8 (HHV-8) infection. Using polymerase chain reaction (PCR) assay HHV-8 sequences were detectable in the lymphoma tissue of both sides. Serologic testing of the patient revealed HHV-8 antibodies in enzyme-linked immunosorbent assay (ELISA) and immunofluorescence assay (IFA). Immunohistologic staining with two antibodies against open reading frame (ORF) 26 and v-cyclin homologues of HHV-8 revealed positive staining of the salivary acinic cells whereas the lymphoma cells were negative. The potential influence of HHV-8 infection for MALT lymphoma development in this case and possible parallels to gastric MALT lymphoma are discussed.

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Year:  2003        PMID： 12653865     DOI： 10.1034/j.1600-0714.2003.00092.x

Source DB:  PubMed          Journal:  J Oral Pathol Med        ISSN： 0904-2512            Impact factor:   4.253


  6 in total

1.  Lymphoma and other malignancies in primary Sjögren's syndrome.

Authors:  S R Pillemer
Journal:  Ann Rheum Dis       Date:  2006-06       Impact factor: 19.103

2.  Macaque homologs of Kaposi's sarcoma-associated herpesvirus (KSHV) infect germinal center lymphoid cells, epithelial cells in skin and gastrointestinal tract and gonadal germ cells in naturally infected macaques.

Authors:  Helle Bielefeldt-Ohmann; A Gregory Bruce; Kellie Howard; Minako Ikoma; Margaret E Thouless; Timothy M Rose
Journal:  Virology       Date:  2018-04-22       Impact factor: 3.616

Review 3.  Lessons from diseases mimicking Sjögren's syndrome.

Authors:  Manuel Ramos-Casals; Pilar Brito-Zerón; Josep Font
Journal:  Clin Rev Allergy Immunol       Date:  2007-06       Impact factor: 8.667

4.  MALT lymphoma in labial salivary gland biopsy from Sjögren syndrome: importance of follow-up in early detection.

Authors:  A Keszler; L I Adler; M S Gandolfo; P A Masquijo Bisio; A C Smith; C F Vollenweider; A M Heidenreich; G de Stefano; M V Kambo; D P Cox; M Narbaitz; H E Lanfranchi
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2012-11-13

5.  Possible Mechanisms of Lymphoma Development in Sjögren's Syndrome.

Authors:  Lingli Dong; Yu Chen; Yasufumi Masaki; Toshiro Okazaki; Hisanori Umehara
Journal:  Curr Immunol Rev       Date:  2013-02

Review 6.  Human herpesvirus 8--a novel human pathogen.

Authors:  Daniel C Edelman
Journal:  Virol J       Date:  2005-09-02       Impact factor: 4.099
  6 in total

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