Literature DB >> 1265296

Prostaglandin E2 in human gingiva in health and disease and its stimulation by female sex steroids.

T M ElAttar.   

Abstract

The levels of prostaglandin E2 were measured by means of radioimmunoassay in 12 clinically normal and 24 chronically inflamed human gingival tissue homogenates. The average values were found to be 16 and 285 pmol/gm wet weight of the normal and inflamed samples, respectively. Addition of estradiol-17beta alone or a mixture of estradiol-17beta and progesterone to incubation media containing normal or inflamed gingiva caused a significant increase in the in vitro synthesis of endogenous PGE2. Increased levels of female sex steroids during pregnancy may enhance gingival inflammation.

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Year:  1976        PMID： 1265296     DOI： 10.1016/0090-6980(76)90155-6

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  10 in total

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2.  Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.

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5.  Urea compounds that increase the biosynthesis of prostaglandins in vivo--in vitro.

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8.  Harmonious functional and aesthetic correction of severe localised pregnancy-induced gingival enlargement associated with capillary haemangioma.

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9.  Endotoxins potentiate COX-2 and RANKL expression in compressed PDL cells.

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Review 10.  Microbial Changes during Pregnancy, Birth, and Infancy.

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  10 in total

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