| Literature DB >> 12652164 |
David Alonso1, Marek W Radomski.
Abstract
Nitric oxide (NO) and endothelin-1 (ET-1) are endothelium-derived mediators that play important roles in vascular homeostasis. This review is focused on the role and reciprocal interactions between NO and ET-1 in health and diseases associated with endothelium dysfunction. We will also discuss the clinical significance of NO donors and drugs that antagonize ET receptors.Entities:
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Year: 2003 PMID: 12652164 DOI: 10.1023/a:1022155206928
Source DB: PubMed Journal: Heart Fail Rev ISSN: 1382-4147 Impact factor: 4.214