Literature DB >> 12652080

Structure of the main ganglioside from the brain of Xenopus laevis.

Angela Maria Rizzo1, Bruno Berra, Federica Rossi, Anna Guerra, Rosalba Gornati, Giovanni Bernardini, Takao Taki, Takeshi Kasama, Laura Mauri, Sandro Sonnino.   

Abstract

The main component of the ganglioside(1) mixture from the brain of the adult amphibian Xenopus laevis accounts for 35% of the total, as lipid bound sialic acid. This ganglioside has been purified and characterized by thin layer chromatography, partial and exhaustive enzymatic hydrolysis with sialidase, TLC-overlay procedures with anti-Gg(4)Cer and anti-Neu5Acalpha6GalNAcbeta specific monoclonal antibodies and mass spectrometry. All together the results suggest the following structure: Neu5Acalpha8Neu5Acalpha3Galbeta3(Neu5Acalpha8Neu5Acalpha6)GalNAcbeta4Galbeta4Glcbeta1Cer, or, IV(3)-alpha-Neu5Ac(2),III(6)-alpha-Neu5Ac(2)-Gg(4)Cer.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12652080     DOI： 10.1023/a:1022584914778

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  17 in total

1.  Restricted occurrence of an unusual ganglioside GD1 alpha in rat brain and its possible involvement in dendritic growth of cerebellar Purkinje neurons.

Authors:  S Furuya; T Hashikawa; Y Hirabayashi
Journal:  J Neurosci Res       Date:  1996-04-01       Impact factor: 4.164

2.  A trisialoganglioside containing a sialyl alpha 2-6 N-acetylgalactosamine residue is a cholinergic-specific antigen, Chol-1 alpha.

Authors:  S Ando; Y Hirabayashi; K Kon; F Inagaki; S Tate; V P Whittaker
Journal:  J Biochem       Date:  1992-03       Impact factor: 3.387

3.  A new procedure for the extraction, purification and fractionation of brain gangliosides.

Authors:  G Tettamanti; F Bonali; S Marchesini; V Zambotti
Journal:  Biochim Biophys Acta       Date:  1973-01-19

4.  Glycolipid patterns during Xenopus embryo development.

Authors:  R Gornati; A M Rizzo; X W Tong; B Berra; G Bernardini
Journal:  Cell Biol Int       Date:  1995-03       Impact factor: 3.612

5.  Structural characterization of a novel cholinergic neuron-specific ganglioside in bovine brain.

Authors:  Y Hirabayashi; T Nakao; F Irie; V P Whittaker; K Kon; S Ando
Journal:  J Biol Chem       Date:  1992-06-25       Impact factor: 5.157

6.  Effect of maternal diet on the distribution of phospholipids and their fatty acid composition in Xenopus laevis embryos.

Authors:  A M Rizzo; R Gornati; F Rossi; G Bernardini; B Berra
Journal:  J Nutr Biochem       Date:  1999-01       Impact factor: 6.048

7.  Ganglioside patterns of frog nervous tissues.

Authors:  M Ohashi
Journal:  Adv Exp Med Biol       Date:  1982       Impact factor: 2.622

8.  A ganglioside of rat ascites hepatoma AH 7974F cells. Occurrence of a novel disialoganglioside (GD1 alpha) with a unique N-acetylneuraminosyl (alpha 2-6)-N-acetylgalactosamine structure.

Authors:  T Taki; Y Hirabayashi; H Ishikawa; S Ando; K Kon; Y Tanaka; M Matsumoto
Journal:  J Biol Chem       Date:  1986-03-05       Impact factor: 5.157

9.  Retinoic acid induces changes in Xenopus embryo glycolipid pattern.

Authors:  A M Rizzo; R Gornati; F Rossi; G Bernardini; B Berra
Journal:  Cell Biol Int       Date:  1995-11       Impact factor: 3.612

10.  A simple and quantitative purification of glycosphingolipids and phospholipids by thin-layer chromatography blotting.

Authors:  T Taki; T Kasama; S Handa; D Ishikawa
Journal:  Anal Biochem       Date:  1994-12       Impact factor: 3.365
View more
  2 in total

1.  Metabolism of vertebrate amino sugars with N-glycolyl groups: resistance of α2-8-linked N-glycolylneuraminic acid to enzymatic cleavage.

Authors:  Leela R L Davies; Oliver M T Pearce; Matthew B Tessier; Siavash Assar; Victoria Smutova; Maria Pajunen; Mizuki Sumida; Chihiro Sato; Ken Kitajima; Jukka Finne; Pascal Gagneux; Alexey Pshezhetsky; Robert Woods; Ajit Varki
Journal:  J Biol Chem       Date:  2012-06-12       Impact factor: 5.157

2.  Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc.

Authors:  Sateesh Peri; Asmita Kulkarni; Felix Feyertag; Patricia M Berninsone; David Alvarez-Ponce
Journal:  Genome Biol Evol       Date:  2018-01-01       Impact factor: 3.416
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.