Literature DB >> 12652007

Model of recovery of locomotor ability after sensorimotor cortex injury in rats.

Larry B Goldstein1.   

Abstract

Animal models of locomotor recovery after brain injury provide tools for understanding the basic neurobiological processes that may underlie recovery after stroke in humans. Measurement of the ability of rats to traverse a narrow elevated beam has proven to be a particularly useful test of locomotor function. Repeated measurement of this behavior over time provides a simple method for quantifying the rate and degree of a rat's locomotor recovery after sensorimotor cortex injury and constitutes a tool for studying its mechanisms and possible treatment strategies. The model has proven particularly useful in predicting the effects of drugs on poststroke recovery in humans.

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Year:  2003        PMID： 12652007     DOI： 10.1093/ilar.44.2.125

Source DB:  PubMed          Journal:  ILAR J        ISSN： 1084-2020


  9 in total

1.  CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury.

Authors:  Shruti V Kabadi; Bogdan A Stoica; Marie Hanscom; David J Loane; Giorgi Kharebava; Michael G Murray Ii; Rainier M Cabatbat; Alan I Faden
Journal:  Neurotherapeutics       Date:  2012-04       Impact factor: 7.620

2.  Recovery of motor deficit, cerebellar serotonin and lipid peroxidation levels in the cortex of injured rats.

Authors:  Antonio Bueno-Nava; Rigoberto Gonzalez-Pina; Alfonso Alfaro-Rodriguez; Vladimir Nekrassov-Protasova; Alfredo Durand-Rivera; Sergio Montes; Fructuoso Ayala-Guerrero
Journal:  Neurochem Res       Date:  2010-06-10       Impact factor: 3.996

3.  Environmental enrichment as a viable neurorehabilitation strategy for experimental traumatic brain injury.

Authors:  Corina O Bondi; Kyle C Klitsch; Jacob B Leary; Anthony E Kline
Journal:  J Neurotrauma       Date:  2014-04-17       Impact factor: 5.269

4.  Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma.

Authors:  Shruti V Kabadi; Bogdan A Stoica; Kimberly R Byrnes; Marie Hanscom; David J Loane; Alan I Faden
Journal:  J Cereb Blood Flow Metab       Date:  2011-08-10       Impact factor: 6.200

5.  Brain injury induces cholesterol 24-hydroxylase (Cyp46) expression in glial cells in a time-dependent manner.

Authors:  Kosara Smiljanic; Irena Lavrnja; Aleksandra Mladenovic Djordjevic; Sabera Ruzdijic; Mirjana Stojiljkovic; Sanja Pekovic; Selma Kanazir
Journal:  Histochem Cell Biol       Date:  2010-06-18       Impact factor: 4.304

6.  The effects of adding prophylactic phenobarbital to therapeutic hypothermia in the term-equivalent hypoxic-ischemic rat.

Authors:  Sushma Krishna; Alexandra Hutton; Eric Aronowitz; Holly Moore; Susan J Vannucci
Journal:  Pediatr Res       Date:  2017-11-22       Impact factor: 3.756

7.  The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats.

Authors:  Jennifer L Walters; Theresa A Lansdell; Keith J Lookingland; Lisa E Baker
Journal:  Toxicol Appl Pharmacol       Date:  2015-10-09       Impact factor: 4.219

8.  Therapeutic effects of eugenol in a rat model of traumatic brain injury: A behavioral, biochemical, and histological study.

Authors:  Jeetprakash Barot; Bhagawati Saxena
Journal:  J Tradit Complement Med       Date:  2021-01-08

9.  Therapeutic hypothermia and hypoxia-ischemia in the term-equivalent neonatal rat: characterization of a translational preclinical model.

Authors:  Shyama D Patel; Leslie Pierce; Amber Ciardiello; Alexandra Hutton; Samuel Paskewitz; Eric Aronowitz; Henning U Voss; Holly Moore; Susan J Vannucci
Journal:  Pediatr Res       Date:  2015-05-21       Impact factor: 3.756
  9 in total

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