Literature DB >> 126506

The in vitro synthesis of 7-hydroxy dehydroepiandrosterone by human mammary tissues.

R A Couch, S J Skinner, C J Tobler, T W Doouss.   

Abstract

Normal and tumorous human mammary tissues were incubated in vitro with [7alpha-3H] dehydroepiandrosterone and [7alpha-3H] dehydroepiandrosterone sulphate. Tritium-labelled 7alpha-hydroxy dehydroepiandrosterone was identified as a principal metabolite from four of the five studies with normal tissue and all seven studies with tumorous tissue.

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Year:  1975        PMID： 126506     DOI： 10.1016/0039-128x(75)90002-1

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  3 in total

1.  Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone.

Authors:  H Lardy; B Partridge; N Kneer; Y Wei
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-03       Impact factor: 11.205

2.  The relationship of urinary and plasma androgens to steroid receptors and menopausal status in breast cancer patients and their influence on survival.

Authors:  B H Mason; I M Holdaway; S J Skinner; R G Kay
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

3.  Effect of hormone manipulation on oxidation, reduction and sulphurylation of dehydroepiandrosterone and oestrone in DMBA-induced rat mammary tumours.

Authors:  K Li; D P Chandra; T Pewnim; T Foo; J B Adams
Journal:  Br J Cancer       Date:  1980-01       Impact factor: 7.640
  3 in total

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