Literature DB >> 12649026

Development of an artificial meniscus using polyvinyl alcohol-hydrogel for early return to, and continuance of, athletic life in sportspersons with severe meniscus injury. I: mechanical evaluation.

Masanori Kobayashi1, Jyunya Toguchida, Masanori Oka.   

Abstract

The importance of knee meniscus function is now recognized, and the treatment of meniscus injury has been changing from resection to repair. However, depending on the type of injury, meniscectomy sometimes cannot be avoided. The young athlete might undergo meniscectomy in order to return to sports life as early as possible. However, in such a knee, it is important to anticipate the future problem of degenerative change or osteoarthrosis. In consideration of the prognosis and circumstances in such patients, we have developed an artificial meniscus using polyvinyl alcohol-hydrogel (PVA-H) and performed mechanical tests for compression and stress-relaxation. We found that the human meniscus has unique viscoelastic properties and a high water content. PVA-H showed viscoelastic behaviour similar to that of human meniscus in mechanical tests. These results suggest that an artificial meniscus using PVA-H with a high water content can compensate for meniscal function and might be clinically applicable.

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Year:  2003        PMID: 12649026     DOI: 10.1016/s0968-0160(02)00152-7

Source DB:  PubMed          Journal:  Knee        ISSN: 0968-0160            Impact factor:   2.199


  6 in total

1.  A multilayer tissue engineered meniscus substitute.

Authors:  Albana Ndreu Halili; Nesrin Hasirci; Vasif Hasirci
Journal:  J Mater Sci Mater Med       Date:  2014-01-23       Impact factor: 3.896

2.  Dynamic compression of human and ovine meniscal tissue compared with a potential thermoplastic elastomer hydrogel replacement.

Authors:  Kristine M Fischenich; Katie Boncella; Jackson T Lewis; Travis S Bailey; Tammy L Haut Donahue
Journal:  J Biomed Mater Res A       Date:  2017-06-27       Impact factor: 4.396

Review 3.  Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration.

Authors:  Weimin Guo; Shuyun Liu; Yun Zhu; Changlong Yu; Shibi Lu; Mei Yuan; Yue Gao; Jingxiang Huang; Zhiguo Yuan; Jiang Peng; Aiyuan Wang; Yu Wang; Jifeng Chen; Li Zhang; Xiang Sui; Wenjing Xu; Quanyi Guo
Journal:  Stem Cells Int       Date:  2015-06-25       Impact factor: 5.443

4.  Functional Characteristics and Mechanical Performance of PCU Composites for Knee Meniscus Replacement.

Authors:  Adijat Omowumi Inyang; Christopher Leonard Vaughan
Journal:  Materials (Basel)       Date:  2020-04-17       Impact factor: 3.623

5.  Biphasic Properties of PVAH (Polyvinyl Alcohol Hydrogel) Reflecting Biomechanical Behavior of the Nucleus Pulposus of the Human Intervertebral Disc.

Authors:  Minhyeok Heo; Seonghun Park
Journal:  Materials (Basel)       Date:  2022-01-31       Impact factor: 3.623

6.  A novel method for the accurate evaluation of Poisson's ratio of soft polymer materials.

Authors:  Jae-Hoon Lee; Sang-Soo Lee; Jun-Dong Chang; Mark S Thompson; Dong-Joong Kang; Sungchan Park; Seonghun Park
Journal:  ScientificWorldJournal       Date:  2013-04-23
  6 in total

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