Literature DB >> 12648806

Hypoglycemic properties of aqueous bark extract of Ceiba pentandra in streptozotocin-induced diabetic rats.

Olusola Ladeji1, Ikechukwu Omekarah, Mariam Solomon.   

Abstract

The claim by Nigerian traditional herbal medicine practitioners that the silk cotton tree, Ceiba pentandra L. Gaertn (Bombacaceae) barks extract has antidiabetic properties was investigated. Diabetes mellitus was induced with streptozotocin and graded doses of the aqueous bark extract were then administered ad libitum in drinking water to the experimentally diabetic rats for 28 days. Administration of the aqueous bark extract caused a statistically significant reduction in plasma glucose level in streptozotocin induced diabetic rats. The extract appeared non-toxic as evidenced by normal serum levels of AST, ALT, ALP and bilirubin. The data appear to support the hypoglycemic effects of C. pentandra. Copyright 2002 Elsevier Science Ireland Ltd.

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Year:  2003        PMID： 12648806     DOI： 10.1016/s0378-8741(02)00321-5

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  9 in total

1.  Antidiabetic effect of Ceiba pentandra extract on streptozotocin-induced non-insulin-dependent diabetic (NIDDM) rats.

Authors:  Paul Désiré D Dzeufiet; Dieudonné Y Ohandja; Léonard Tédong; Emmanuel Acha Asongalem; Théophile Dimo; Selestin D Sokeng; Pierre Kamtchouing
Journal:  Afr J Tradit Complement Altern Med       Date:  2006-08-28

2.  Hypoglycemic and antihyperglycemic effect of Ceiba pentandra L. Gaertn in normal and streptozotocin-induced diabetic rats.

Authors:  R J Satyaprakash; M S Rajesh; M Bhanumathy; M S Harish; T N Shivananda; H N Shivaprasad; G Sushma
Journal:  Ghana Med J       Date:  2013-09

3.  Antioxidant activity and free radical scavenging capacity of phenolic extracts from Helicteres isora L. and Ceiba pentandra L.

Authors:  Nataraj Loganayaki; Perumal Siddhuraju; Sellamuthu Manian
Journal:  J Food Sci Technol       Date:  2011-05-05       Impact factor: 2.701

4.  Comparative toxicity, phytochemistry, and use of 53 Philippine medicinal plants.

Authors:  Lydia M Clemen-Pascual; Rene Angelo S Macahig; Nina Rosario L Rojas
Journal:  Toxicol Rep       Date:  2021-12-10

5.  Protective Effect of Urtica dioica L. (Urticaceae) on Morphometric and Morphologic Alterations of Seminiferous Tubules in STZ Diabetic Rats.

Authors:  Mohammad Jafar Golalipour; Babak Kabiri Balajadeh; Soraya Ghafari; Ramin Azarhosh; Vahid Khori
Journal:  Iran J Basic Med Sci       Date:  2011-09       Impact factor: 2.699

6.  Antidiabetic Properties of Azardiracta indica and Bougainvillea spectabilis: In Vivo Studies in Murine Diabetes Model.

Authors:  Menakshi Bhat; Sandeepkumar K Kothiwale; Amruta R Tirmale; Shobha Y Bhargava; Bimba N Joshi
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-18       Impact factor: 2.629

7.  Assessment of phytochemicals and antioxidant activities of raw and germinating Ceiba pentandra (kapok) seeds.

Authors:  Chekuboyina Ravi Kiran; Dadi Bhaskara Rao; Nagala Sirisha; Tamanam Raghava Rao
Journal:  J Biomed Res       Date:  2013-09-28

8.  Hypoglycemic Properties of the Aqueous Extract from the Stem Bark of Ceiba pentandra in Dexamethasone-Induced Insulin Resistant Rats.

Authors:  Christian Kuété Fofié; Elvine Pami Nguelefack-Mbuyo; Nole Tsabang; Albert Kamanyi; Télesphore Benoît Nguelefack
Journal:  Evid Based Complement Alternat Med       Date:  2018-09-16       Impact factor: 2.629

9.  Aqueous Bark Extract of Ceiba speciosa (A. St.-Hill) Ravenna Protects against Glucose Toxicity in Caenorhabditis elegans.

Authors:  Fabrine Bianchin Dos Santos; Caroline Brandão Quines; Luiz Eduardo Ben Pilissão; Ana Helena de Castro Dal Forno; Cristiane Freitas Rodrigues; Cristiane Casagrande Denardin; Fabiane Moreira Farias; Daiana Silva Ávila
Journal:  Oxid Med Cell Longev       Date:  2020-10-08       Impact factor: 6.543
  9 in total

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