Literature DB >> 12648337

Management of gallstone disease in the elderly.

J D R Arthur1, P R Edwards, L S Chagla.   

Abstract

AIM: To determine the outcome of management of symptomatic gallstone disease (GSD) in patients aged 80 years or more. PATIENTS AND METHODS: A retrospective review of the outcome of 79 patients admitted to 2 district general hospitals with symptomatic GSD over a 1-year period was undertaken. Patients were grouped according to method of management: non-operative, ERCP, and cholecystectomy. POSSUM scores for the ERCP and cholecystectomy groups were calculated and observed, and predicted outcome compared.
RESULTS: Obstructive jaundice and biliary colic were the most common presenting symptoms. Each patient had been admitted at least once before the study period (median, 2; range, 1-3). Outcomes are detailed in Table 1. Non-operative management failed in 18 of 23 patients, with 17.4% mortality. ERCP was successful in 40 of 47 patients with 3 complications (0.24 of predicted) and no mortality. In all, 11 laparoscopic and 12 open cholecystectomies were performed with 6 complications and 1 mortality (0.95 and 0.83 of predicted, respectively): 4 complications and the only death occurring after emergency cholecystectomy. Table 1 Outcomes Management Number Mortality Morbidity Outcome Non-operative 23 4 9 5 OK, 13 re-admitted, 4 still symptomatic ERCP 47 0 3 1 PTC, 6 operated Operative 23 1 6
CONCLUSIONS: This study suggests that recurrent GSD in elderly patients managed non-operatively may have fatal outcome. Elective cholecystectomy has acceptable morbidity and mortality in this age group and there is often ample opportunity to avoid emergency surgery, but a prospective randomised study is required to improve clinical algorithms.

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Year:  2003        PMID: 12648337      PMCID: PMC1963712          DOI: 10.1308/003588403321219849

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  15 in total

1.  Routine laparoscopic cholecystectomy after endoscopic sphincterotomy for choledocholithiasis in octogenarians: is it worth the risk?

Authors:  R Costi; D DiMauro; A Mazzeo; A S Boselli; S Contini; V Violi; L Roncoroni; L Sarli
Journal:  Surg Endosc       Date:  2006-11-16       Impact factor: 4.584

2.  Expectant treatment of cholecystectomy after endoscopic retrograde cholangiopancreatography for choledocholithiasis in patients over 80 years of age.

Authors:  R Costi; L Sarli; V Violi; L Roncoroni
Journal:  Surg Endosc       Date:  2005-09-26       Impact factor: 4.584

3.  Expectant treatment or cholecystectomy after endoscopic retrograde cholangiopancreatography for choledocholithiasis in patients over 80 years old?

Authors:  C M Pring; L Skelding-Millar; R J R Goodall
Journal:  Surg Endosc       Date:  2005-01-10       Impact factor: 4.584

4.  The risk paradox: use of elective cholecystectomy in older patients is independent of their risk of developing complications.

Authors:  Taylor S Riall; Deepak Adhikari; Abhishek D Parmar; Suzanne K Linder; Francesca M Dimou; Winston Crowell; Nina P Tamirisa; Courtney M Townsend; James S Goodwin
Journal:  J Am Coll Surg       Date:  2014-12-17       Impact factor: 6.113

5.  Gallstone disease in the elderly: are older patients managed differently?

Authors:  Simon Bergman; Nadia Sourial; Isabelle Vedel; Wael C Hanna; Shannon A Fraser; Daniel Newman; Aaron J Bilek; Christos Galatas; Jonah E Marek; Johanne Monette
Journal:  Surg Endosc       Date:  2010-05-29       Impact factor: 4.584

6.  Recurrence of biliary disease following non-operative management in elderly patients.

Authors:  Simon Bergman; Mohammed Al-Bader; Nadia Sourial; Isabelle Vedel; Wael C Hanna; Aaron J Bilek; Christos Galatas; Jonah E Marek; Shannon A Fraser
Journal:  Surg Endosc       Date:  2015-02-12       Impact factor: 4.584

7.  Usefulness of gallbladder ejection fraction estimation to predict the recurrence of biliary pain in patients with symptomatic gallstones who did not undergo cholecystectomy.

Authors:  Sung Noh Hong; Jong Kyun Lee; Kyu Taek Lee; Jin Seok Heo; Seong Ho Choi; Poong Lyul Rhee; Seung Woon Paik; Byung Chul Yoo; Jong Chul Rhee
Journal:  Dig Dis Sci       Date:  2004-05       Impact factor: 3.199

8.  Cost-effectiveness of elective laparoscopic cholecystectomy versus observation in older patients presenting with mild biliary disease.

Authors:  Abhishek D Parmar; Mark D Coutin; Gabriela M Vargas; Nina P Tamirisa; Kristin M Sheffield; Taylor S Riall
Journal:  J Gastrointest Surg       Date:  2014-06-12       Impact factor: 3.452

9.  Trends in Follow-Up of Patients Presenting to the Emergency Department with Symptomatic Cholelithiasis.

Authors:  Francesca M Dimou; Deepak Adhikari; Hemalkumar B Mehta; Taylor S Riall
Journal:  J Am Coll Surg       Date:  2015-12-21       Impact factor: 6.113

10.  PREOP-Gallstones: A Prognostic Nomogram for the Management of Symptomatic Cholelithiasis in Older Patients.

Authors:  Abhishek D Parmar; Kristin M Sheffield; Deepak Adhikari; Robert A Davee; Gabriela M Vargas; Nina P Tamirisa; Yong-Fang Kuo; James S Goodwin; Taylor S Riall
Journal:  Ann Surg       Date:  2015-06       Impact factor: 12.969

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