Literature DB >> 12646927

Drug target validation: Hitting the target.

Caitlin Smith.   

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Year:  2003        PMID: 12646927     DOI: 10.1038/422341a

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  15 in total

1.  Identification and validation of inhibitor-responsive kinase substrates using a new paradigm to measure kinase-specific protein phosphorylation index.

Authors:  Xiang Li; Varsha Rao; Jin Jin; Bin Guan; Kenna L Anderes; Charles J Bieberich
Journal:  J Proteome Res       Date:  2012-06-18       Impact factor: 4.466

2.  Leveraging Big Data to Transform Drug Discovery.

Authors:  Benjamin S Glicksberg; Li Li; Rong Chen; Joel Dudley; Bin Chen
Journal:  Methods Mol Biol       Date:  2019

3.  An integrated approach for identification and target validation of antifungal compounds active against Erg11p.

Authors:  Dominic Hoepfner; Shantanu Karkare; Stephen B Helliwell; Martin Pfeifer; Markus Trunzer; Sophie De Bonnechose; Alfred Zimmerlin; Jianshi Tao; Daryl Richie; Andreas Hofmann; Stefan Reinker; Mathias Frederiksen; N Rao Movva; Jeffrey A Porter; Neil S Ryder; Christian N Parker
Journal:  Antimicrob Agents Chemother       Date:  2012-05-21       Impact factor: 5.191

4.  Elucidation of the molecular mechanisms of a salicylhydrazide class of compounds by proteomic analysis.

Authors:  Xuefei Cao; Carmen Plasencia; Atsuko Kanzaki; Austin Yang; Terrence R Burke; Nouri Neamati
Journal:  Curr Cancer Drug Targets       Date:  2009-03       Impact factor: 3.428

5.  A conceptual review on systems biology in health and diseases: from biological networks to modern therapeutics.

Authors:  Pramod Rajaram Somvanshi; K V Venkatesh
Journal:  Syst Synth Biol       Date:  2013-09-18

6.  Two-stage flux balance analysis of metabolic networks for drug target identification.

Authors:  Zhenping Li; Rui-Sheng Wang; Xiang-Sun Zhang
Journal:  BMC Syst Biol       Date:  2011-06-20

7.  A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer.

Authors:  Shih-Heng Yeh; Hsiang-Yuan Yeh; Von-Wun Soo
Journal:  J Clin Bioinforma       Date:  2012-01-13

Review 8.  Complementary Approaches to Existing Target Based Drug Discovery for Identifying Novel Drug Targets.

Authors:  Suhas Vasaikar; Pooja Bhatia; Partap G Bhatia; Koon Chu Yaiw
Journal:  Biomedicines       Date:  2016-11-21

9.  Discovery of Boolean metabolic networks: integer linear programming based approach.

Authors:  Yushan Qiu; Hao Jiang; Wai-Ki Ching; Xiaoqing Cheng
Journal:  BMC Syst Biol       Date:  2018-04-11

10.  An IPTG Inducible Conditional Expression System for Mycobacteria.

Authors:  Sudha Ravishankar; Anisha Ambady; Haripriya Ramu; Naina Vinay Mudugal; Ragadeepthi Tunduguru; Anand Anbarasu; Umender K Sharma; Vasan K Sambandamurthy; Sudha Ramaiah
Journal:  PLoS One       Date:  2015-08-06       Impact factor: 3.240

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