Literature DB >> 12646151

Lamellipodia protrusion: moving interactions of vinculin and Arp2/3.

Susan W Craig1, Hui Chen.   

Abstract

A direct, transient interaction between vinculin and Arp2/3 is required to promote receptor-stimulated lamellipodial extension and cell spreading. Vinculin selectively recruits Arp2/3 to the leading edge of the lamellipodium, where it may couple the actin polymerization machinery to adhesion complexes to promote membrane protrusion over ruffling.

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Year:  2003        PMID： 12646151     DOI： 10.1016/s0960-9822(03)00160-x

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  10 in total

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2.  v-Crk regulates membrane dynamics and Rac activation.

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Review 4.  Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions.

Authors:  Joanne M Leerberg; Alpha S Yap
Journal:  Protoplasma       Date:  2012-12-29       Impact factor: 3.356

5.  Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness.

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Review 7.  Dynamics between actin and the VE-cadherin/catenin complex: novel aspects of the ARP2/3 complex in regulation of endothelial junctions.

Authors:  Abdallah Abu Taha; Hans-J Schnittler
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8.  Morphology, cytoskeletal organization, and myosin dynamics of mouse embryonic fibroblasts cultured on nanofibrillar surfaces.

Authors:  Ijaz Ahmed; Abdul S Ponery; Alam Nur-E-Kamal; Jabeen Kamal; Adam S Meshel; Michael P Sheetz; Melvin Schindler; Sally Meiners
Journal:  Mol Cell Biochem       Date:  2007-02-09       Impact factor: 3.842

9.  The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.

Authors:  Erumbi S Rangarajan; Tina Izard
Journal:  Int J Mol Sci       Date:  2021-01-11       Impact factor: 5.923

10.  HAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells.

Authors:  Qiang Liang; Qing Han; Wan Huang; Gang Nan; Bao-Qing Xu; Jian-Li Jiang; Zhi-Nan Chen
Journal:  PLoS One       Date:  2014-07-17       Impact factor: 3.240
  10 in total

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