Literature DB >> 12644771

Transitional cell carcinoma of the urinary bladder metastatic to the orbit.

Nicoletta Fynn-Thompson1, James M McKiernan, Aaron Fay.   

Abstract

We report a rare case of transitional cell carcinoma of the urinary bladder metastatic to the orbit, review the histopathology, and highlight characteristics of the few previously reported cases. A 68-year-old man with a remote history of transitional cell carcinoma of the urinary bladder presented with decreased visual acuity, afferent pupillary defect, and limited extraocular motility OS. Computed tomography scan of the orbits showed a diffuse infiltrate surrounding the left globe and optic nerve. Biopsy revealed metastatic transitional cell carcinoma. The patient expired one month later. With only seven cases previously reported, we conclude that transitional cell carcinoma of the urinary bladder rarely metastasizes to the orbit. When present, orbital metastases signify aggressive disease and a poor prognosis. Mean survival following orbital diagnosis is 2.2 months in the cases reported.

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Year:  2003        PMID: 12644771     DOI: 10.1097/01.IOP.0000056026.84209.1B

Source DB:  PubMed          Journal:  Ophthalmic Plast Reconstr Surg        ISSN: 0740-9303            Impact factor:   1.746


  5 in total

1.  Metastasis to the orbit from transitional cell carcinoma of the bladder.

Authors:  Keigo Shikishima; Akira Miyake; Isao Ikemoto; Makio Kawakami
Journal:  Jpn J Ophthalmol       Date:  2006 Sep-Oct       Impact factor: 2.447

Review 2.  Orbital Metastasis From Urothelial Carcinoma: A Comprehensive Literature Review.

Authors:  Bonnie A Sklar; Kalla A Gervasio; Konstantin Karmazin; Albert Y Wu
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2019 May/Jun       Impact factor: 1.746

3.  [Palliative radiotherapy for a retrobulbar metastasis from a urinary bladder carcinoma].

Authors:  F Zwicker; K Herfarth; J Debus
Journal:  Ophthalmologe       Date:  2008-02       Impact factor: 1.059

4.  Solitary cerebral metastasis from transitional cell carcinoma after a 14-year remission of urinary bladder cancer treated with gemcitabine: Case report and literature review.

Authors:  J Manuel Sarmiento; Matt S Wi; Zhe Piao; Eric S Stiner
Journal:  Surg Neurol Int       Date:  2012-07-28

5.  Renal transitional cell carcinoma with bilateral ocular metastasis in a cat.

Authors:  Irit Grader; Teresa L Southard; Marjorie H Neaderland
Journal:  JFMS Open Rep       Date:  2016-07-14
  5 in total

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