Literature DB >> 12643606

Schatzki's rings do not protect against acid reflux and may decrease esophageal acid clearance.

George R Winters1, Corinne L Maydonovitch, Roy K H Wong.   

Abstract

Schatzki's rings (SR) are a common cause of intermittent solid food dysphagia, but their etiology is unclear. Many believe they are related to acid reflux, hypothesizing that the rings act as a protective barrier against further reflux. The purpose of this study was to determine whether dilation of SR affected the degree of acid reflux. Twenty patients participated in the study. All patients underwent esophageal manometry and 24-hr pH monitoring off all acid inhibitory medications before and two weeks after esophageal dilation. No significant differences were noted in any of the reflux parameters measured before and after dilation. However, there was a trend toward reduction in symptom score in all patients, a decrease in Johnson-DeMeester score, and a decrease in supine reflux time in patients with thick SR after dilation. There was no correlation between ring diameter and the presence or absence of reflux. In conclusion, Schatzki's rings do not prevent esophageal reflux, and they may act to decrease esophageal acid clearance, especially in the supine position, thereby increasing esophageal acid exposure.

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Year:  2003        PMID: 12643606     DOI: 10.1023/a:1021975309951

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  25 in total

1.  THE ANATOMIC BASIS FOR THE LOWER ESOPHAGEAL CONTRACTION RING. PLICATION THEORY AND ITS APPLICATIONS.

Authors:  O A STIENNON
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1963-10

2.  Dysphagia due to a diaphragm-like localized narrowing in the lower esophagus (lower esophageal ring).

Authors:  R SCHATZKI; J E GARY
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1953-12

Review 3.  Lower esophageal ring. 2.

Authors:  R K Goyal; J J Glancy; H M Spiro
Journal:  N Engl J Med       Date:  1970-06-11       Impact factor: 91.245

Review 4.  Progress in gastroenterology. Esophagus.

Authors:  P Kramer
Journal:  Gastroenterology       Date:  1968-06       Impact factor: 22.682

Review 5.  The lower esophageal ring.

Authors:  J A Rinaldo
Journal:  Gastroenterology       Date:  1966-12       Impact factor: 22.682

6.  The lower esophageal ring and esophageal reflux.

Authors:  B F Scharschmidt; H D Watts
Journal:  Am J Gastroenterol       Date:  1978-05       Impact factor: 10.864

7.  Anatomic location of the lower esophageal ring.

Authors:  J H Johnston; J C Griffin
Journal:  Surgery       Date:  1967-04       Impact factor: 3.982

8.  Correlation of lower esophageal mucosal ring and 24-h pH monitoring of the esophagus.

Authors:  D J Ott; M S Ledbetter; M Y Chen; J A Koufman; D W Gelfand
Journal:  Am J Gastroenterol       Date:  1996-01       Impact factor: 10.864

9.  Drug-induced esophageal strictures.

Authors:  L Bonavina; T R DeMeester; L McChesney; W Schwizer; M Albertucci; R T Bailey
Journal:  Ann Surg       Date:  1987-08       Impact factor: 12.969

10.  A comparison of five maintenance therapies for reflux esophagitis.

Authors:  S Vigneri; R Termini; G Leandro; S Badalamenti; M Pantalena; V Savarino; F Di Mario; G Battaglia; G S Mela; A Pilotto
Journal:  N Engl J Med       Date:  1995-10-26       Impact factor: 91.245

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  1 in total

1.  Schatzki ring and Barrett's esophagus: do they occur together?

Authors:  Marcia C Mitre; David A Katzka; Colleen M Brensinger; James D Lewis; Ricardo J Mitre; Gregory G Ginsberg
Journal:  Dig Dis Sci       Date:  2004-05       Impact factor: 3.199

  1 in total

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