Literature DB >> 12643191

Mechanisms involved in platelet hyperactivation and platelet-endothelium interrelationships in diabetes mellitus.

Mariella Trovati1, Giovanni Anfossi.   

Abstract

This article discusses the recent findings about the mechanisms involved in platelet hyperactivation in diabetes mellitus. Particular attention is focused on the advances pertaining to 1) new features of platelet activation; 2) the role of calcium fluxes; 3) the role of glucose, insulin, and insulin resistance; 4) the role of nitric oxide; and 5) the role of endothelium.

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Year:  2002        PMID: 12643191     DOI: 10.1007/s11892-002-0020-7

Source DB:  PubMed          Journal:  Curr Diab Rep        ISSN: 1534-4827            Impact factor:   4.810


  36 in total

Review 1.  Influence of insulin and of insulin resistance on platelet and vascular smooth muscle cell function.

Authors:  Mariella Trovati; Giovanni Anfossi
Journal:  J Diabetes Complications       Date:  2002 Jan-Feb       Impact factor: 2.852

2.  Regulation of protein kinase C by short term hyperglycaemia in human platelets in vivo and in vitro.

Authors:  R Assert; G Scherk; A Bumbure; V Pirags; H Schatz; A F Pfeiffer
Journal:  Diabetologia       Date:  2001-02       Impact factor: 10.122

Review 3.  Nitric oxide insufficiency, platelet activation, and arterial thrombosis.

Authors:  J Loscalzo
Journal:  Circ Res       Date:  2001-04-27       Impact factor: 17.367

4.  Tumor necrosis factor-alpha inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells.

Authors:  Ahmad Aljada; Husam Ghanim; Ezzat Assian; Paresh Dandona
Journal:  Metabolism       Date:  2002-04       Impact factor: 8.694

5.  Catecholamines, via beta-adrenoceptors, increase intracellular concentrations of 3',5'-cyclic guanosine monophosphate (cGMP) through nitric oxide in human platelets.

Authors:  Giovanni Anfossi; Isabella Russo; Paola Massucco; Luigi Mattiello; Mariella Trovati
Journal:  Thromb Haemost       Date:  2002-03       Impact factor: 5.249

6.  Platelet antioxidant enzymes in insulin-dependent diabetes mellitus.

Authors:  G Seghieri; P Di Simplicio; R Anichini; L Alviggi; A De Bellis; F Bennardini; F Franconi
Journal:  Clin Chim Acta       Date:  2001-07-05       Impact factor: 3.786

7.  Administration of glutathione in patients with type 2 diabetes mellitus increases the platelet constitutive nitric oxide synthase activity and reduces PAI-1.

Authors:  V Martina; G A Bruno; E Zumpano; C Origlia; L Quaranta; G P Pescarmona
Journal:  J Endocrinol Invest       Date:  2001-01       Impact factor: 4.256

8.  Endothelial perturbation in children and adolescents with type 1 diabetes: association with markers of the inflammatory reaction.

Authors:  M Romano; M Pomilio; S Vigneri; A Falco; P L Chiesa; F Chiarelli; G Davì
Journal:  Diabetes Care       Date:  2001-09       Impact factor: 19.112

9.  The possible association of in vivo leukocyte-platelet heterophilic aggregate formation and the development of diabetic angiopathy.

Authors:  M Kaplar; J Kappelmayer; A Veszpremi; K Szabo; M Udvardy
Journal:  Platelets       Date:  2001-11       Impact factor: 3.862

Review 10.  Insulin resistance and vascular function.

Authors:  Alain D Baron
Journal:  J Diabetes Complications       Date:  2002 Jan-Feb       Impact factor: 2.852

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  5 in total

1.  Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome.

Authors:  James P Smith; Elias V Haddad; Mary B Taylor; Denise Oram; Dana Blakemore; Qingxia Chen; Olivier Boutaud; John A Oates
Journal:  Hypertension       Date:  2012-02-06       Impact factor: 10.190

2.  The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects.

Authors:  S L Spinelli; J J O'Brien; S Bancos; G M Lehmann; D L Springer; N Blumberg; C W Francis; M B Taubman; R P Phipps
Journal:  PPAR Res       Date:  2008       Impact factor: 4.964

3.  Mediation Effect of Platelet Traits on Associations of Central Obesity with Aging Biomarkers in Rural Adults of Henan, China.

Authors:  Xinwei Chen; Ruiying Li; Xiaoyu Hou; Yuqin Wang; Mingming Pan; Ning Kang; Yinghao Yuchi; Wei Liao; Xiaotian Liu; Zhenxing Mao; Wenqian Huo; Chongjian Wang; Jian Hou
Journal:  Nutrients       Date:  2022-08-31       Impact factor: 6.706

Review 4.  The prothrombotic tendency in metabolic syndrome: focus on the potential mechanisms involved in impaired haemostasis and fibrinolytic balance.

Authors:  Isabella Russo
Journal:  Scientifica (Cairo)       Date:  2012-08-30

Review 5.  Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles.

Authors:  Katie L Lannan; Julie Sahler; Nina Kim; Sherry L Spinelli; Sanjay B Maggirwar; Olivier Garraud; Fabrice Cognasse; Neil Blumberg; Richard P Phipps
Journal:  Front Immunol       Date:  2015-02-13       Impact factor: 7.561

  5 in total

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