Literature DB >> 12640404

Retinopathy of prematurity in practice. I: screening for threshold disease.

R Brennan1, L Gnanaraj, D G Cottrell.   

Abstract

AIMS: To review an 11-year period of screening for retinopathy of prematurity (ROP) in the north of England by a single ophthalmologist. To identify the gestational ages and birth weights of babies reaching different stages of ROP. To investigate the workload involved in screening to detect threshold ROP, and that the practical outcomes had narrower inclusion criteria for screening. To identify babies treated for threshold disease.
METHODS: During the period August 1987-October 1998, babies were screened according to the national guidelines and the results were prospectively entered onto a computerised database. These data were then systematically reviewed.
RESULTS: Data were available for 484 babies: 203 (41.9%) developed any ROP, 46 (9.5%) reached stage 3 ROP, and 25 (5.2%) reached threshold and were treated. Data on 425 babies showed them to require an average of 2.3 screening examinations per baby. It took an average of 39 screening examinations to detect one case of threshold ROP. The more premature and lighter birth weight babies required the most examinations. Therefore, restricting the inclusion criteria for screening would only have reduced the total number of screenings modestly and could have allowed us to miss two of our threshold cases who were both of 30 weeks gestational age and >1400 g birth weight.
CONCLUSIONS: Screening is time consuming but worthwhile in view of the benefits of treatment. As applied to babies in the north of England, the current national screening criteria are satisfactory. The results of treatment of the babies identified in this study are presented in the accompanying paper.

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Year:  2003        PMID: 12640404     DOI: 10.1038/sj.eye.6700296

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  7 in total

1.  [Comparison of the anatomical and functional outcome after laser or cryotherapy for retinopathy of prematurity (ROP)].

Authors:  C Jandeck; U Kellner; H Heimann; M H Foerster
Journal:  Ophthalmologe       Date:  2005-01       Impact factor: 1.059

2.  Is there a role for high-frequency ultrasonography in clinical staging of retinopathy of prematurity?

Authors:  Danny H Kauffinann Jokl; Ronald H Silverman; Sheri L Nemerofiky; Steven A Kane; Michael F Chiang; Robert Lopez; Grace Lee
Journal:  J Pediatr Ophthalmol Strabismus       Date:  2006 Jan-Feb       Impact factor: 1.402

3.  [Ophthalmological screening for retinopathy of prematurity].

Authors:  I Oberacher-Velten; H Segerer; H Helbig
Journal:  Ophthalmologe       Date:  2012-12       Impact factor: 1.059

4.  UK population based study of severe retinopathy of prematurity: screening, treatment, and outcome.

Authors:  L Haines; A R Fielder; H Baker; A R Wilkinson
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2005-05       Impact factor: 5.747

5.  The local vasoconstriction of infant's skin following instillation of mydriatic eye drops.

Authors:  Atilla Alpay; Bahri Ermis; Silay C Ugurbas; Fatih Battal; Haci Murat Sagdik
Journal:  Eur J Clin Pharmacol       Date:  2010-09-11       Impact factor: 2.953

6.  Do we need India-specific retinopathy of prematurity screening guidelines?

Authors:  Santosh G Honavar
Journal:  Indian J Ophthalmol       Date:  2019-06       Impact factor: 1.848

7.  Retinopathy of prematurity screening in the Indian population: it's time to set our own guidelines!

Authors:  Vasumathy Vedantham
Journal:  Indian J Ophthalmol       Date:  2007 Sep-Oct       Impact factor: 1.848

  7 in total

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