Literature DB >> 1263767

Relationship between desaturation and chain elongation of palmityl-CoA in rat liver microsomes.

M Nakagawa, Y Kawashima, M Uchiyama.   

Abstract

The relationship between desaturation and chain elongation of palmityl-CoA was studied in rat liver microsomes. Enzyme activities for desaturation and chain elongation were stimulated by re-feeding starved rats. The activities of desaturation and chain elongation in re-fed rats were four- and twofold greater than those in normal rats, respectively. When a sonicated dispersion of lecithin was added to the incubation medium containing both reactions, chain elongation activity, especially formation of stearic acid, was stimulated and desaturation activity was apparently depressed.

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Year:  1976        PMID: 1263767     DOI: 10.1007/BF02532864

Source DB:  PubMed          Journal:  Lipids        ISSN: 0024-4201            Impact factor:   1.880


  15 in total

1.  Some factors affecting chain elongation of palmityl-CoA in rat liver microsomes.

Authors:  M Nakagawa; Y Kawashima; M Uchiyama
Journal:  Chem Pharm Bull (Tokyo)       Date:  1976-01       Impact factor: 1.645

2.  [Method of purification of lecithins (phosphatidylcholines)].

Authors:  M FAURE
Journal:  Bull Soc Chim Biol (Paris)       Date:  1950

3.  The enzymic chain elongation of fatty acids by rat-liver microsomes.

Authors:  D H Nugteren
Journal:  Biochim Biophys Acta       Date:  1965-10-04

4.  Stimulation of stearoyl-CoA desaturase activity by sn-glycero-3-phosphate in mouse liver microsomes.

Authors:  P K Raju; R Reiser
Journal:  Biochim Biophys Acta       Date:  1972-10-05

5.  The influence of dietary alterations, fasting and competitive interactions on the microsomal chain elongation of fatty acids.

Authors:  H Sprecher
Journal:  Biochim Biophys Acta       Date:  1974-08-22

6.  Chain elongation of linoleic acid and its inhibition by other fatty acids in vitro.

Authors:  H Mohrhauer; K Christiansen; M V Gan; M Deubig; R T Holman
Journal:  J Biol Chem       Date:  1967-10-10       Impact factor: 5.157

7.  A requirement for lipids by the microsomal stearyl coenzyme A desaturase.

Authors:  P D Jones; P W Holloway; R O Peluffo; S J Wakil
Journal:  J Biol Chem       Date:  1969-02-25       Impact factor: 5.157

8.  Effect of organophosphate pesticides on lecithin-cholesterol acyltransferase in human plasma.

Authors:  M Nakagawa; M Uchiyama
Journal:  Biochem Pharmacol       Date:  1974-05-01       Impact factor: 5.858

9.  The desaturation step in the animal biosynthesis of polyunsaturated fatty acids.

Authors:  R R Brenner
Journal:  Lipids       Date:  1971-08       Impact factor: 1.880

10.  Mechanisms of fatty acid synthesis in rat-liver microsomes.

Authors:  C Landriscina; G V Gnoni; E Quagliariello
Journal:  Biochim Biophys Acta       Date:  1970-05-05
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  4 in total

1.  Different effects of fibrates on the microsomal fatty acid chain elongation and the acyl composition of phospholipids in guinea-pigs.

Authors:  M Vázquez; M Alegret; M López; C Rodríguez; T Adzet; M Merlos; J C Laguna
Journal:  Br J Pharmacol       Date:  1995-12       Impact factor: 8.739

2.  Dietary control of the chain elongation of palmityl-CoA in rat liver microsomes.

Authors:  Y Kawashima; Y Suzuki; Y Hashimoto
Journal:  Lipids       Date:  1977-05       Impact factor: 1.880

3.  The effects of fat-free, saturated and polyunsaturated fat diets on rat liver and plasma lipids.

Authors:  G J Nelson; D S Kelley; P C Schmidt; C M Serrato
Journal:  Lipids       Date:  1987-02       Impact factor: 1.880

4.  Alterations by peroxisome proliferators of acyl composition of hepatic phosphatidylcholine in rats, mice and guinea-pigs. Role of stearoyl-CoA desaturase.

Authors:  Y Kawashima; A Hirose; H Kozuka
Journal:  Biochem J       Date:  1986-04-01       Impact factor: 3.857

  4 in total

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